Evidence map›Paper›PMID 31878127›Full record

ArticlePlants (Basel, Switzerland)2019

Antitumor Potential and Phytochemical Profile of Plants from Sardinia (Italy), a Hotspot for Biodiversity in the Mediterranean Basin.

Concettina Cappadone, Manuela Mandrone, Ilaria Chiocchio, Cinzia Sanna, Emil Malucelli, Vincenza Bassi, Giovanna Picone, Ferruccio Poli

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Plants (Basel, Switzerland) · 2024
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  7. Use of Strawberry Tree (Foods (Basel, Switzerland) · 2022
    Review
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  9. Article
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  11. Article
  12. Leaves and Fruits Preparations ofAntibiotics (Basel, Switzerland) · 2021
    Review
  13. Review
  14. Chemical Composition and Plant Growth ofMolecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Concettina CappadoneDepartment of Pharmacy and Biotechnology, University of Bologna, via San Donato 19/2, 40127 Bologna, Italy.
Manuela MandroneDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio, 42, 40126 Bologna, Italy.ORCID 0000-0002-0541-390X
Ilaria ChiocchioDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio, 42, 40126 Bologna, Italy.
Cinzia SannaDepartment of Life and Environmental Sciences, University of Cagliari, Via Sant'Ignazio da Laconi 13, 09123 Cagliari, Italy.
Emil MalucelliDepartment of Pharmacy and Biotechnology, University of Bologna, via San Donato 19/2, 40127 Bologna, Italy.ORCID 0000-0002-1077-0098
Vincenza BassiDepartment of Pharmacy and Biotechnology, University of Bologna, via San Donato 19/2, 40127 Bologna, Italy.
Giovanna PiconeDepartment of Pharmacy and Biotechnology, University of Bologna, via San Donato 19/2, 40127 Bologna, Italy.
Ferruccio PoliDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio, 42, 40126 Bologna, Italy.
University of Bologna · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sardinia (Italy), with its wide range of habitats and high degree of endemism, is an important area for plant-based drug discovery studies. In this work, the antitumor activity of 35 samples from Sardinian plants was evaluated on human osteosarcoma cells U2OS. The results showed that five plants were strongly antiproliferative:

Indexed as

antitumor activityapoptosiscell cycleNMR profilingSardinian plantssesquiterpene lactones

Identifiers

PMID31878127
PMCPMC7020228
OpenAlexW2995078799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.