Evidence map›Paper›PMID 31878048›Full record

ArticleMarine drugs2019

Novel Efficient Bioprocessing of Marine Chitins into Active Anticancer Prodigiosin.

Van Bon Nguyen, Shan-Ping Chen, Thi Hanh Nguyen, Minh Trung Nguyen, Thi Thanh Thao Tran, Chien Thang Doan, Thi Ngoc Tran, Anh Dzung Nguyen, Yao-Haur Kuo, San-Lang Wang

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Van Bon NguyenDivision of Computational Mathematics and Engineering, Institute for Computational Science, Ton Duc Thang University, Ho Chi Minh City 700000, Vietnam.ORCID 0000-0002-2666-9584
Shan-Ping ChenDepartment of Chemistry, Tamkang University, New Taipei City 25137, Taiwan.
Thi Hanh NguyenInstitute of Biotechnology and Environment, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.
Minh Trung NguyenDepartment of Science and Technology, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.ORCID 0000-0002-1405-2923
Thi Thanh Thao TranDepartment of Science and Technology, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.
Chien Thang DoanDepartment of Science and Technology, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.ORCID 0000-0002-9379-0923
Thi Ngoc TranDepartment of Science and Technology, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.
Anh Dzung NguyenInstitute of Biotechnology and Environment, Tay Nguyen University, Buon Ma Thuot 630000, Vietnam.ORCID 0000-0003-2335-1084
Yao-Haur KuoDivision of Chinese Materia Medica Development, National Research Institute of Chinese Medicine, Taipei 11221, Taiwan.
San-Lang WangDepartment of Chemistry, Tamkang University, New Taipei City 25137, Taiwan.ORCID 0000-0002-1384-3731
Thai Nguyen University · VNTamkang University · TWNational Research Institute of Chinese Medicine · TWTon Duc Thang University · VN

Funding

Ministry of Science and Technology, Taiwan MOST 106-106-2320-B-032-001-MY3
6 · The paper itself

Abstract

Marine chitins (MC) have been utilized for the production of vast array of bioactive products, including chitooligomers, chitinase, chitosanase, antioxidants, anti-NO, and antidiabetic compounds. The aim of this study is the bioprocessing of MC into a potent anticancer compound, prodigiosin (PG), via microbial fermentation. This bioactive compound was produced by

Indexed as

A549 CellsAntineoplastic AgentsChitinColonic NeoplasmsFermentationHep G2 CellsHumansMCF-7 CellsProdigiosinAntineoplastic AgentsChitinProdigiosinanti-tumorsbioprocessingprodigiosinSerratia marcescensα-Chitin

Identifiers

PMID31878048
PMCPMC7024390
OpenAlexW2996586986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.