Evidence map›Paper›PMID 31877995›Full record

ReviewMolecules (Basel, Switzerland)2019

Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan-A Critical Review.

Hongjie Yuan, Ping Lan, Yan He, Chengliang Li, Xia Ma

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 94 citations in OpenAlex.

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  19. Molecules (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hongjie YuanSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China.
Ping LanGuangxi Key Laboratory of Polysaccharide Materials and Modification, School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530008, China.
Yan HeSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China.
Chengliang LiLB Cosmeceutical Technology Co., Ltd., Shanghai 201499, China.
Xia MaSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China.
Shanghai Institute of Technology · CNGuangxi University for Nationalities · CN

Funding

Shanghai Alliance "Solubilization and activity evaluation of yeast β-glucan" ,Guangxi Key Laboratory of Polysaccharide Materials and Modification No. GXPSMM18YB-010). No. LM201963 ;No. GXPSMM18YB-010
6 · The paper itself

Abstract

β-Glucan exhibits many biological activities and functions such as stimulation of the immune system and anti-inflammatory, anti-microbial, anti-infective, anti-viral, anti-tumor, anti-oxidant, anti-coagulant, cholesterol-lowering, radio protective, and wound healing effects. It has a wide variety of uses in pharmaceutical, cosmetic, and chemical industries as well as in food processing units. However, due to its dense triple helix structure, formed by the interaction of polyhydroxy groups in the β-d-glucan molecule, it features poor solubility, which not only constrains its applications, but also inhibits its physiological function in vivo. One aim is to expand the applications for modified β-glucan with potential to prevent disease, various therapeutic purposes and as health-improving ingredients in functional foods and cosmetics. This review introduces the major modification methods required to understand the bioactivity of β-glucan and critically provides a literature survey on the structural features of this molecule and reported biological activity. We also discuss a new method to create novel opportunities to exploit maximally various properties of β-glucan, namely ultrasound-assisted enzymatic modification.

Indexed as

Chemical PhenomenaMolecular Structurebeta-GlucansHumansSolubilityViscositybeta-Glucansanti-oxidationbiological activityfunctionsmodificationpolysaccharidessolubleβ-glucan

Identifiers

PMID31877995
PMCPMC6983044
OpenAlexW2996086584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.