Evidence map›Paper›PMID 31877991›Full record

ReviewCells2019

TRPC Channels in Proteinuric Kidney Diseases.

Gentzon Hall, Liming Wang, Robert F Spurney

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Functional Evaluation ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Genotype-phenotype correlations and clinical outcomes of genetic TRPC6 podocytopathies.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Observational
  6. Article
  7. The CaPediatric nephrology (Berlin, Germany) · 2025
    Review
  8. The Life of a Kidney Podocyte.Acta physiologica (Oxford, England) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. A Putative Role for TRPC6 in Immune-Mediated Kidney Injury.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gentzon HallDivision of Nephrology, Department of Medicine, Duke University; Durham, NC 27710, USA.
Liming WangDivision of Nephrology, Department of Medicine, Duke University; Durham, NC 27710, USA.
Robert F SpurneyDivision of Nephrology, Department of Medicine, Duke University; Durham, NC 27710, USA.
Durham Technical Community College · US

Funding

Role of Gq Signaling in Promoting Podocyte Injury in Diabetes MellitusR01DK087707 · NIDDK · DUKE UNIVERSITY · PI SPURNEY, ROBERT · 2011 to 2014
$1.4M
The Role of Interleukin-15 Receptor-alpha Variants in the Pathogenesis of FSGSK08DK111940 · NIDDK · DUKE UNIVERSITY · PI HALL, GENTZON · 2017 to 2021
$794k
BLRD VA I01 BX002984Juvenile Diabetes Research Foundation United States of America 1-INO-2015-94-A-BNIDDK NIH HHS K08 DK111940NIDDK NIH HHS R01 DK087707NIH HHS K08 DK111940NIH HHS R01 DK087707NIMHD NIH HHS L60 MD008562Veterans Administration Merit Review Program BX002984
6 · The paper itself

Abstract

Over a decade ago, mutations in the gene encoding

Indexed as

Diabetic NephropathiesFibrosisGlomerulosclerosis, Focal SegmentalHumansKidneyKidney DiseasesProteinuriaRenal Insufficiency, ChronicTRPC6 Cation ChannelTRPC Cation ChannelsTRPC6 Cation ChannelTRPC Cation Channelschronic kidney diseasediabetic kidney diseasediabetic nephropathyfocal segmental glomerulosclerosistransient receptor potential canonical channeltransient receptor potential cation channelTRPC3TRPC5TRPC6TRPC channel

Identifiers

PMID31877991
PMCPMC7016871
OpenAlexW2994635267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.