Evidence map›Paper›PMID 31877982›Full record

ArticleCells2019

Neutrophil Extracellular Traps (NETs) in the Cerebrospinal Fluid Samples from Children and Adults with Central Nervous System Infections.

Daniel Appelgren, Helena Enocsson, Barbro H Skogman, Marika Nordberg, Linda Perander, Dag Nyman, Clara Nyberg, Jasmin Knopf, Luis E Muñoz, Christopher Sjöwall and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  10. Article
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  12. Neutrophils in oncolytic virus immunotherapy.Frontiers in immunology · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Role of NETosis in Central Nervous System Injury.Oxidative medicine and cellular longevity · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Daniel AppelgrenDivision of Drug Research, Department of Medical and Health Sciences, Linköping University, SE-581 85 Linköping, Sweden.ORCID 0000-0002-3328-5060
Helena EnocssonDivision of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden.ORCID 0000-0002-2125-2931
Barbro H SkogmanCenter for Clinical Research Dalarna-Uppsala University, Region Dalarna and Faculty of Medicine and Health Sciences, Örebro University, SE-702 81 Örebro, Sweden.
Marika NordbergÅland Central Hospital, Department of Infectious Diseases, AX-22 100 Mariehamn, Åland, Finland.
Linda PeranderÅland Central Hospital, Department of Infectious Diseases, AX-22 100 Mariehamn, Åland, Finland.
Dag NymanBimelix AB, AX-22 100 Mariehamn, Åland, Finland.
Clara NybergÅland Central Hospital, Department of Infectious Diseases, AX-22 100 Mariehamn, Åland, Finland.
Jasmin KnopfDepartment of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), DE-91 054 Erlangen, Germany.
Luis E MuñozDepartment of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), DE-91 054 Erlangen, Germany.ORCID 0000-0002-5395-804X
Christopher SjöwallDivision of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden.ORCID 0000-0003-0900-2048
Johanna SjöwallClinic of Infectious Diseases, Linköping University Hospital, SE-581 85 Linköping, Sweden.ORCID 0000-0001-5622-866X
Linköping University · SEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUppsala University · SE

Funding

CSRD VA 1EU (H2020-MSCE-RISE-2015) project 690836 PANGGerman Research Foundation project GRK-1660Region Östergötland (ALF Grants) LIO-791961Swedish Rheumatism Association R-844801Volkswagen-Stiftung 90361
6 · The paper itself

Abstract

Neutrophils operate as part of the innate defence in the skin and may eliminate the

Indexed as

AdolescentAdultAgedAged, 80 and overBiomarkersCentral Nervous System InfectionsChemokines, CXCChildChild, PreschoolExtracellular TrapsFemaleHumansLyme NeuroborreliosisMaleMiddle AgedNeutrophilsBiomarkersChemokines, CXCadultsborreliacentral nervous systemcerebrospinal fluidchemokineschildrencytokinesinfectionneutrophil extracellular trapsvirus

Identifiers

PMID31877982
PMCPMC7016761
OpenAlexW2995120640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.