Evidence map›Paper›PMID 31877959›Full record

Trial reportInternational journal of molecular sciences2019

Identification and Functional Characterization of

Hsiang-Yu Lin, Ru-Yi Tu, Schu-Rern Chern, Yun-Ting Lo, Sisca Fran, Fang-Jie Wei, Sung-Fa Huang, Shin-Yu Tsai, Ya-Hui Chang, Chung-Lin Lee and 2 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Review
  3. Cellular crosstalk between endothelial and vascular smooth muscle cells via the BACH1/COL3A1 axis promotes vascular calcification in chronic kidney disease.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  4. Article
  5. Novel Phenotypic Insights into theInternational journal of neonatal screening · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Epidemiology of Mucopolysaccharidoses Update.Diagnostics (Basel, Switzerland) · 2021
    Review
  17. Effect of MutatedDiagnostics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Hsiang-Yu LinDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.ORCID 0000-0002-9619-0990
Ru-Yi TuDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Schu-Rern ChernDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Yun-Ting LoRare Disease Center, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Sisca FranDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Fang-Jie WeiDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Sung-Fa HuangDepartment of Laboratory Medicine, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Shin-Yu TsaiRare Disease Center, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Ya-Hui ChangRare Disease Center, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Chung-Lin LeeDepartment of Pediatrics, MacKay Memorial Hospital, Hsinchu 30071, Taiwan.
Shuan-Pei LinDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.
Chih-Kuang ChuangDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City 25160, Taiwan.ORCID 0000-0001-9776-2092
Mackay Memorial Hospital · TWChina Medical University · TWFu Jen Catholic University · TWNational Taipei University of Nursing and Health Science · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hunter syndrome (mucopolysaccharidosis II; MPS II) is caused by a defect of the iduronate-2-sulfatase (

Indexed as

Mucopolysaccharidosis IIMutation, MissenseAsian PeopleFemaleGlycoproteinsHumansInfantMaleSequence Analysis, DNATaiwanGlycoproteinsIDS protein, humanCOS-7 cell transfectiongenotype–phenotype correlation.Hunter syndromeIDS enzyme activityiduronate-2-sulfatase (IDS) genemucopolysaccharidosis II (MPS II)

Identifiers

PMID31877959
PMCPMC6982257
OpenAlexW2996307640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.