ArticleMetabolites2019
Different Sources of Copper Effect on Intestinal Epithelial Cell: Toxicity, Oxidative Stress, and Metabolism.
Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Effects of Copper Glycinate Replacing High-Dose Copper Sulfate on Growth Performance, Trace Element Metabolism and Stem Cell Activity in Growing Pigs.Biological trace element research · 2026Article
- Copper Complexes: Emerging Micro- and Nanosystems for Dermatological Treatment.Pharmaceutics · 2026Review
- Level and Source of Copper Affects Gene Expression of Copper-Regulatory Proteins and Soluble and Mucosal Copper Concentrations in the Small Intestine of Weanling Pigs.Animals : an open access journal from MDPI · 2026Article
- Effects of Copper Citrate and Copper Sulfate on Intestinal Health, Muscle Fiber Traits, and Antioxidant Capacity in Weaned Pigs.Animals : an open access journal from MDPI · 2026Article
- Review
- Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.NPJ biofilms and microbiomes · 2026Article
- Article
- Ionomics-metabolome association analysis as a new approach to the impact of dietary copper levels in suckling piglets model.Scientific reports · 2023Article
- Optimisation of trace mineral supplementation in diets for Atlantic salmon smolt with reference to holistic fish performance in terms of growth, health, welfare, and potential environmental impacts.Frontiers in physiology · 2023Article
- Porcine and Chicken Intestinal Epithelial Cell Models for Screening Phytogenic Feed Additives-Chances and Limitations in Use as Alternatives to Feeding Trials.Microorganisms · 2022Review
- Different copper sources and levels affect growth performance, copper content, carcass characteristics, intestinal microorganism and metabolism of finishing pigs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Dietary Copper Improves Intestinal Morphology via Modulating Intestinal Stem Cell Activity in Pigs.Animals : an open access journal from MDPI · 2021Article
- Excessive copper in feed not merely undermines animal health but affects food safety.Journal of veterinary science · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Copper (Cu) is widely used in the swine industry to improve the growth performance of pigs. However, high doses of copper will induce cell damage and toxicity. The aim of this study was to evaluate toxicity, bioavailability, and effects on metabolic processes of varying copper sources using porcine intestinal epithelial cells (IPEC-J2) as a model. The IPEC-J2 were treated with two doses (30 and 120 μM) of CuSO
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.