Evidence map›Paper›PMID 31877910›Full record

Trial reportInternational journal of environmental research and public health2019

Feasibility, Safety and Efficacy of a Virtual Reality Exergame System to Supplement Upper Extremity Rehabilitation Post-Stroke: A Pilot Randomized Clinical Trial and Proof of Principle.

Nahid Norouzi-Gheidari, Alejandro Hernandez, Philippe S Archambault, Johanne Higgins, Lise Poissant, Dahlia Kairy

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 14 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 14 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Pooled it
  4. Virtual Reality Therapy for Upper Limb Motor Impairments in Patients With Stroke: A Systematic Review and Meta-Analysis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Serious games for upper limb rehabilitation after stroke: a meta-analysis.Journal of neuroengineering and rehabilitation · 2021
    Pooled it
  13. Pooled it
  14. Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2017
    Pooled it
  15. Trial
  16. Trial
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nahid Norouzi-GheidariSchool of Physical and Occupational Therapy, McGill University, Montreal, QC H3G 1Y5, Canada.ORCID 0000-0001-9623-7712
Alejandro HernandezCRIR Research Centre, IURDPM site of CIUSSS-Montreal, Montreal, QC H3S 2J4, Canada.
Philippe S ArchambaultSchool of Physical and Occupational Therapy, McGill University, Montreal, QC H3G 1Y5, Canada.
Johanne HigginsCRIR Research Centre, IURDPM site of CIUSSS-Montreal, Montreal, QC H3S 2J4, Canada.ORCID 0000-0003-1513-6587
Lise PoissantCRIR Research Centre, IURDPM site of CIUSSS-Montreal, Montreal, QC H3S 2J4, Canada.ORCID 0000-0002-4925-6352
Dahlia KairyCRIR Research Centre, IURDPM site of CIUSSS-Montreal, Montreal, QC H3S 2J4, Canada.ORCID 0000-0001-6872-6607
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal · CAJewish Rehabilitation Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Increasing the amount of therapy time has been shown to improve motor function in stroke survivors. However, it is often not possible to increase the amount of therapy time provided in the current one-on-one therapy models. Rehabilitation-based virtual reality exergame systems, such as Jintronix, can be offered to stroke survivors as an adjunct to traditional therapy. The goal of this study was to examine the safety and feasibility of providing additional therapy using an exergame system and assess its preliminary clinical efficacy. (2) Methods: Stroke survivors receiving outpatient rehabilitation services participated in this pilot randomized control trial in which the intervention group received 4 weeks of exergaming sessions in addition to traditional therapy sessions. (3) Results: Nine subjects in the intervention and nine subjects in the control group completed the study. The intervention group had at least two extra sessions per week, with an average duration of 44 min per session and no serious adverse events (falls, dizziness, or pain). The efficacy measures showed statistically meaningful improvements in the activities of daily living measures (i.e., MAL-QOM (motor activity log-quality of movement) and both mobility and physical domains of the SIS (stroke impact scale) with mean difference of 1.0%, 5.5%, and 6.7% between the intervention and control group, respectively) at post-intervention. (4) Conclusion: Using virtual reality exergaming technology as an adjunct to traditional therapy is feasible and safe in post-stroke rehabilitation and may be beneficial to upper extremity functional recovery.

Indexed as

Stroke RehabilitationUpper ExtremityVirtual RealityActivities of Daily LivingAdultAgedExerciseFeasibility StudiesFemaleHumansMaleMiddle AgedOutpatientsPilot ProjectsRecovery of FunctionSingle-Blind MethodexergamesKinectrehabilitationstrokeupper extremityvideo gamesvirtual reality

Identifiers

PMID31877910
PMCPMC6981843
OpenAlexW2995171966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.