Evidence map›Paper›PMID 31877821›Full record

ArticlePharmaceutics2019

MRI/Photoluminescence Dual-Modal Imaging Magnetic PLGA Nanocapsules for Theranostics.

Yajie Zhang, Miguel García-Gabilondo, Anna Rosell, Anna Roig

Abstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanoencapsulation of vitamin BJournal of food science · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Biomimetic cell membrane-coated poly(lactic-Bioengineering & translational medicine · 2023
    Review
  9. Article
  10. Article
  11. PLGA-Based Composites for Various Biomedical Applications.International journal of molecular sciences · 2022
    Review
  12. Endovascular administration of magnetized nanocarriers targeting brain delivery after stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  13. Review
  14. Review
  15. Nano-Medicine in the Cardiovascular System.Frontiers in pharmacology · 2021
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yajie ZhangInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus UAB, 08193 Bellaterra, Catalonia, Spain.ORCID 0000-0003-1566-1007
Miguel García-GabilondoNeurovascular Research Laboratory, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, 08035 Barcelona, Catalonia, Spain.ORCID 0000-0002-2015-2621
Anna RosellNeurovascular Research Laboratory, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, 08035 Barcelona, Catalonia, Spain.
Anna RoigInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus UAB, 08193 Bellaterra, Catalonia, Spain.ORCID 0000-0001-6464-7573

Funding

China Scholarship Council 201606330068European Regional Development Fund AC17/00004 grantGeneralitat de Catalunya 2017SGR765 & 2017SGR1427Ministerio de Ciencia e Innovación PCIN-2017-090, CTQ2017-87637-R, SAF2017-87670-R, SEV-2015-0496, MDM-2017-0720
6 · The paper itself

Abstract

Developing multifunctional and biocompatible drug delivery nanoplatforms that integrate high drug loads and multiple imaging modalities avoiding cross-interferences is extremely challenging. Here we report on the successful chemical reaction of the high quantum yield biodegradable and photoluminescent polyester (BPLP) with the poly(lactic-co-glycolic acid) (PLGA) polymer to fabricate biocompatible photoluminescent nanocapsules (NCs). Furthermore, we transform the PLGA-BPLP NCs into a magnetic resonance (MR)/photoluminescence dual-modal imaging theranostic platform by incorporating superparamagnetic iron oxide nanoparticles (SPIONs) into the polymeric shell. In vitro phantoms confirmed the excellent MRI-r

Indexed as

drug delivery systemsmagnetic resonance imagingmagnetic targetingmultimodal imagingphotoluminescencePLGA nanocapsulestheranostics

Identifiers

PMID31877821
PMCPMC7023350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.