ArticleCancers2019
Rectum Dose Constraints for Carbon Ion Therapy: Relative Biological Effectiveness Model Dependence in Relation to Clinical Outcomes.
Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Dose-Volume Constraints for Thoracic, Abdominal, and Pelvic Carbon Ion Radiotherapy: A Literature Review.Cancer medicine · 2025Review
- Article
- Mixed- and multi-relative biological effectiveness model simultaneous optimization in carbon ion radiotherapy: A proof-of-concept.Physics and imaging in radiation oncology · 2024Article
- A deep learning model for predicting the modified micro-dosimetric kinetic model-based dose and the dose-averaged linear energy transfer for prostate cancer in carbon ion therapy.Physics and imaging in radiation oncology · 2024Article
- Correlation between dose-volume parameters and rectal bleeding after 12 fractions of carbon ion radiotherapy for prostate cancer.World journal of radiology · 2024Article
- The sensitivity of radiobiological models in carbon ion radiotherapy (CIRT) and its consequences on the clinical treatment plan: Differences between LEM and MKM models.Journal of applied clinical medical physics · 2024Article
- Variation of the relative biological effectiveness in the penumbra of ion therapy beams estimated using different microdosimetric approaches.Physics and imaging in radiation oncology · 2024Article
- Article
- Validation of the relative biological effectiveness of active-energy scanning carbon-ion radiotherapy on a commercial treatment planning system with a microdosimetic kinetic model.Radiation oncology (London, England) · 2023Article
- Dose-volume constraints for head-and-neck cancer in carbon ion radiotherapy: A literature review.Cancer medicine · 2023Review
- Comparison of dosimetries of carbon-ion pencil beam scanning, proton pencil beam scanning and volumetric modulated arc therapy for locally recurrent rectal cancer.Journal of radiation research · 2023Article
- Conversion and validation of rectal constraints for prostate carcinoma receiving hypofractionated carbon-ion radiotherapy with a local effect model.Radiation oncology (London, England) · 2021Article
- Dosimetric Impact of Inter-Fraction Anatomical Changes in Carbon Ion Boost Treatment for High-Risk Prostate Cancer (AIRC IG 14300).Frontiers in oncology · 2021Article
- RBE-weighted dose conversions for patients with recurrent nasopharyngeal carcinoma receiving carbon-ion radiotherapy from the local effect model to the microdosimetric kinetic model.Radiation oncology (London, England) · 2020Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical application of different relative biological effectiveness (RBE) models for carbon ion RBE-weighted dose calculation hinders a global consensus in defining normal tissue constraints. This work aims to update the local effect model (LEM)-based constraints for the rectum using microdosimetric kinetic model (mMKM)-defined values, relying on RBE translation and the analysis of long-term clinical outcomes. LEM-optimized plans of treated patients, having suffered from prostate adenocarcinoma (
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