ArticleInternational journal of molecular sciences2019
The Impact of Glycosylation of Osteopontin on Urinary Stone Formation.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Pathological and therapeutic implications of Notch overexpression in claudin-low breast cancers.Human cell · 2026Article
- Correlation Between Urinary Osteopontin Concentration and the Mineral Content and Composition of Kidney Stones.Journal of clinical medicine · 2025Article
- Study protocol for a randomized single-center cross-over study: Dapagliflozin treatment in recurring kidney stone patients.PloS one · 2025Article
- The immune duality of osteopontin and its therapeutic implications for kidney transplantation.Frontiers in immunology · 2025Review
- SGLT2 Inhibitors and Their Effect on Urolithiasis: Current Evidence and Future Directions.Journal of clinical medicine · 2024Review
- Comparison of cat stone matrix and cat urine proteomes to human calcium oxalate stone matrix and urine proteomes.Urolithiasis · 2024Article
- Impact of Sodium-Glucose Cotransporter-2 Inhibitors on Urolithiasis.Kidney international reports · 2023Article
- Aberrant glycosylation of osteopontin in a rat renal stone formation model: A preliminary study.BJUI compass · 2023Article
- Delineating the Role of the Urinary Metabolome in the Lithogenesis of Calcium-Based Kidney Stones.Urology · 2022Article
- Identification of the pivotal role of SPP1 in kidney stone disease based on multiple bioinformatics analysis.BMC medical genomics · 2022Article
- A large staghorn stone diagnosed and managed in an asymptomatic patient using the "Kidney Injury Test (Kit)" spot urine assay: A case report.Urology case reports · 2021Article
- Recent advances on the mechanisms of kidney stone formation (Review).International journal of molecular medicine · 2021Review
- Narrative review of urinary glycan biomarkers in prostate cancer.Translational andrology and urology · 2021Review
- Deciphering the O-Glycosylation of HKU1 Spike Protein With the Dual-Functional Hydrophilic Interaction Chromatography Materials.Frontiers in chemistry · 2021Article
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
Osteopontin (OPN) is a matrix glycoprotein of urinary calculi. This study aims to identify the role of aberrant glycosylation of OPN in urolithiasis. We retrospectively measured urinary glycosylated OPN normalized by urinary full-length-OPN levels in 110 urolithiasis patients and 157 healthy volunteers and 21 patients were prospectively longitudinal follow-up during stone treatment. The urinary full-length-OPN levels were measured using enzyme-linked immunosorbent assay and glycosylated OPN was measured using a lectin array and lectin blotting. The assays were evaluated using the area under the receiver operating characteristics curve to discriminate stone forming urolithiasis patients. In the retrospective cohort, urinary Gal3C-S lectin reactive- (Gal3C-S-) OPN/full-length-OPN, was significantly higher in the stone forming urolithiasis patients than in the healthy volunteers (
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