ReviewNutrients2019
The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review.Nutrients · 2023Pooled it
- How gait influences frailty models and health-related outcomes in clinical-based and population-based studies: a systematic review.Journal of cachexia, sarcopenia and muscle · 2021Pooled it
- The OMNIVEG Study: Effects of Transitioning from a Traditional to a Vegan Mediterranean Diet on Fat Oxidation During Exercise.Nutrients · 2025Trial
- The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial.BMC medicine · 2023Trial
- Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial.Clinical epigenetics · 2021Trial
- Nutritional Status and Cardiovascular Disease in Older Adults: Clinical Perspectives from Mechanisms to Management.Journal of clinical medicine · 2026Review
- Associations between Mediterranean diet adherence and body composition and metabolic outcomes in older adults at risk of sarcopenic obesity.BMC geriatrics · 2026Article
- The association between the planetary health diet index (PHDI) and muscular dystrophies: A mediating role of phenotypic age.Medicine · 2026Article
- Dietary Responses to Non-Communicable Chronic Disease Diagnoses-A Scoping Review.International journal of general medicine · 2026Review
- Health-Promoting Potential of the Mediterranean Diet and Challenges for Its Application in Aging Populations.Nutrients · 2025Review
- Article
- Participation in Healthy Ageing Centres in Bosnia and Herzegovina Is Associated with Increased Physical Activity, Social Interactions, and Life Satisfaction Among Older People: A Cross-Sectional Study.Journal of ageing and longevity · 2025Article
- From bench to bedside: translational insights into aging research.Frontiers in aging · 2025Review
- Cognitive dysfunction-an under looked avenue to promote health in incarcerated elderly population through yoga.Frontiers in human neuroscience · 2025Article
- Appendicular Skeletal Muscle Index Is Positively Related to Mediterranean Diet Adherence in University Students.Diseases (Basel, Switzerland) · 2024Article
- An unbiased, sustainable, evidence-informed Universal Food Guide: a timely template for national food guides.Nutrition journal · 2024Review
- Association between Mediterranean Diet and Advanced Glycation End Products in University Students: A Cross-Sectional Study.Nutrients · 2024Article
- Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS).BMC medicine · 2024Article
- Aging and Inflammation.Cold Spring Harbor perspectives in medicine · 2024Review
- Determinants for Mediterranean diet adherence beyond the boundaries: a cross-sectional study from Sharjah, the United Arab Emirates.Journal of translational medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aging population is rapidly increasing all over the world. This results in significant implications for the planning and provision of health and social care. Aging is physiologically characterized by a decrease in lean mass, bone mineral density and, to a lesser extent, fat mass. The onset of sarcopenia leads to weakness and a further decrease in physical activity. An insufficient protein intake, which we often observe in patients of advanced age, certainly accelerates the progression of sarcopenia. In addition, many other factors (e.g., insulin resistance, impaired protein digestion and absorption of amino acids) reduce the stimulation of muscle protein synthesis in the elderly, even if the protein intake is adequate. Inadequate intake of foods can also cause micronutrient deficiencies that contribute to the development of frailty. We know that a healthy eating style in middle age predisposes to so-called "healthy and successful" aging, which is the condition of the absence of serious chronic diseases or of an important decline in cognitive or physical functions, or mental health. The Mediterranean diet is recognized to be a "healthy food" dietary pattern; high adherence to this dietary pattern is associated with a lower incidence of chronic diseases and lower physical impairment in old age. The aim of our review was to analyze observational studies (cohort and case-control studies) that investigated the effects of following a healthy diet, and especially the effect of adherence to a Mediterranean diet (MD), on the progression of aging and on onset of frailty.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.