ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2020
Test-retest reliability of the N2 event-related potential in school-aged children with autism spectrum disorder (ASD).
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Effects of a Nonwearable Digital Therapeutic Intervention on Preschoolers With Autism Spectrum Disorder in China: Open-Label Randomized Controlled Trial.Journal of medical Internet research · 2023Trial
- Reliability of short interval cortical inhibition in children with attention deficit hyperactivity disorder.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Effects of a Session of Exergames and Traditional Games on Inhibitory Control in Children With Autism Spectrum Disorder: Randomized Controlled Crossover Trial.JMIR serious games · 2025Article
- Stability, change, and reliable individual differences in electroencephalography measures: A lifespan perspective on progress and opportunities.NeuroImage · 2023Review
- Looking Back at the Next 40 Years of ASD Neuroscience Research.Journal of autism and developmental disorders · 2021Review
- Looking for consistency in an uncertain world: test-retest reliability of neurophysiological and behavioral readouts in autism.Journal of neurodevelopmental disorders · 2021Article
- Atypical Neural Responses of Cognitive Flexibility in Parents of Children With Autism Spectrum Disorder.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThe N2 ERP component is used as a biomeasure of executive function in children with autism spectrum disorder (ASD). The aim of the current study was to evaluate the test-retest reliability of N2 amplitude in this population.
methodsERPs were recorded from 7 to 11-year-old children with ASD during Flanker (n = 21) and Go/Nogo tasks (n = 14) administered at two time points separated by approximately three months. Reliability of the N2 component was examined using intraclass correlation coefficients (ICCs).
resultsReliability for mean N2 amplitude obtained during the Flanker task was moderate (congruent: ICC = 0.542, 95% CI [0.173, 0.782]; incongruent: ICC = 0.629, 95% CI [0.276, 0.831]). Similarly, reliability for the Go/Nogo task ranged from moderate to good ('go': ICC = 0.817, 95% CI [0.535, 0.937]; 'nogo': ICC = 0.578, 95% CI [0.075, 0.843]).
conclusionsThese findings support the use of N2 amplitude as a biomeasure of executive function in school-aged children with ASD. SIGNIFICANCE: This research addresses a critical gap in clinical neurophysiology, as an understanding of the stability and reliability of the N2 component is needed in order to differentiate variance explained by repeated measurement versus targeted treatments and interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.