Evidence map›Paper›PMID 31877417›Full record

ArticleEBioMedicine2020

Cortical haemodynamic response measured by functional near infrared spectroscopy during a verbal fluency task in patients with major depression and borderline personality disorder.

Syeda F Husain, Tong-Boon Tang, Rongjun Yu, Wilson W Tam, Bach Tran, Travis T Quek, Shi-Hui Hwang, Cheryl W Chang, Cyrus S Ho, Roger C Ho

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in EBioMedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 78 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 4 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 4 syntheses or guidelines pooled it, 143 citations in OpenAlex.

  1. Nonsuicidal self-injury and rumination: A meta-analysis.Journal of clinical psychology · 2023
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Syeda F HusainInstitute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Tong-Boon TangCentre for Intelligent Signal and Imaging Research (CISIR), University Teknologi PETRONAS, Perak, Malaysia.
Rongjun YuDepartment of Psychology, Faculty of Arts and Social Science, National University of Singapore, Singapore.
Wilson W TamAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Bach TranJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam; Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.
Travis T QuekDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Shi-Hui HwangDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cheryl W ChangDepartment of Psychological Medicine, National University Health System, Singapore.
Cyrus S HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Roger C HoInstitute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: pcmrhcm@nus.edu.sg.
National University of Singapore · SGNational University Health System · SGTrường ĐH Nguyễn Tất Thành · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional near infrared spectroscopy (fNIRS) provides a direct and quantitative assessment of cortical haemodynamic function during a cognitive task. This functional neuroimaging modality may be used to elucidate the pathophysiology of psychiatric disorders, and identify neurophysiological differences between co-occurring psychiatric disorders. However, fNIRS research on borderline personality disorder (BPD) has been limited. Hence, this study aimed to compare cerebral haemodynamic function in healthy controls (HC), patients with major depressive disorder (MDD) and patients with BPD.

methodsfNIRS signals during a verbal fluency task designed for clinical assessment was recorded for all participants. Demographics, clinical history and symptom severity were also noted.

findingsCompared to HCs (n = 31), both patient groups (MDD, n = 31; BPD, n = 31) displayed diminished haemodynamic response in the frontal, temporal and parietal cortices. Moreover, haemodynamic response in the right frontal cortex is markedly lower in patients with MDD compared to patients with BPD.

interpretationNormal cortical function in patients with BPD is disrupted, but not as extensively as in patients with MDD. These results provide further neurophysiological evidence for the distinction of patients with MDD from patients with BPD.

Indexed as

Neuropsychological TestsSpectroscopy, Near-InfraredTask Performance and AnalysisAdultAgedBorderline Personality DisorderFemaleHemodynamicsHumansMajor Depressive DisorderMaleMiddle AgedPrefrontal CortexYoung AdultBorderline personality disorderHaemodynamic responseMajor depressive disorderNear-infrared spectroscopyPrefrontal cortexVerbal fluency task

Identifiers

PMID31877417
PMCPMC6938854
OpenAlexW2997272625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.