Evidence map›Paper›PMID 31877028›Full record

ArticleACS chemical biology2020

Catalytic Cycle of Glycoside Hydrolase BglX from

Kiran V Mahasenan, María T Batuecas, Stefania De Benedetti, Choon Kim, Neha Rana, Mijoon Lee, Dusan Hesek, Jed F Fisher, Julia Sanz-Aparicio, Juan A Hermoso and 1 more

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Crystal structure ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Enzymes that catalyze cyclization of β-1,2-glucans.Applied microbiology and biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Periplasmic β-glucosidase BglX fromInternational journal of biochemistry and molecular biology · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Kiran V MahasenanDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.
María T BatuecasDepartment of Crystallography and Structural Biology , Institute of Physical Chemistry "Rocasolano", CSIC , 28006 Madrid , Spain.
Stefania De BenedettiDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.
Choon KimDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.ORCID 0000-0003-0306-8935
Neha RanaDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.ORCID 0000-0002-2259-6306
Mijoon LeeDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.ORCID 0000-0001-7432-0427
Dusan HesekDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.
Jed F FisherDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.
Julia Sanz-AparicioDepartment of Crystallography and Structural Biology , Institute of Physical Chemistry "Rocasolano", CSIC , 28006 Madrid , Spain.
Juan A HermosoDepartment of Crystallography and Structural Biology , Institute of Physical Chemistry "Rocasolano", CSIC , 28006 Madrid , Spain.ORCID 0000-0002-1862-8950
Shahriar MobasheryDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , Indiana 46556 , United States.ORCID 0000-0002-7695-7883
University of Notre Dame · USInstituto de Química Física Blas Cabrera · ES

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
Penicillin-Binding Proteins, Mechanism and InhibitionR01GM061629 · NIGMS · WAYNE STATE UNIVERSITY · PI MOBASHERY, SHAHRIAR · 2001 to 2018
$5.1M
Cell-Wall Recycling and Nexus to Antibiotic ResistanceR35GM131685 · NIGMS · UNIVERSITY OF NOTRE DAME · PI MOBASHERY, SHAHRIAR · 2019 to 2023
$1.9M
NIDDK NIH HHS P30 DK089507NIGMS NIH HHS R01 GM061629NIGMS NIH HHS R35 GM131685
6 · The paper itself

Abstract

BglX is a heretofore uncharacterized periplasmic glycoside hydrolase (GH) of the human pathogen

Indexed as

BiofilmsCatalysisCatalytic DomainCell MembraneCrystallography, X-RayGene Expression RegulationGlycoside HydrolasesHumansHydrolysisModels, MolecularMutationPeptidoglycanPolysaccharidesProtein BindingProtein MultimerizationPseudomonas aeruginosaGlycoside HydrolasesPeptidoglycanPolysaccharides

Identifiers

PMID31877028
PMCPMC7995829
OpenAlexW2998158933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.