ArticleJournal of the Chinese Medical Association : JCMA2020
Albumin supplementation may have limited effects on prolonged hypoalbuminemia in major burn patients: An outcome and prognostic factor analysis.
Article in Journal of the Chinese Medical Association : JCMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Preoperative Glucose-Albumin Ratio and Its Association with Postoperative Outcomes in Critically Ill Adult Burn Patients: A Retrospective Cohort Study of 1119 Patients.Diagnostics (Basel, Switzerland) · 2026Article
- The Efficacy of Albumin Infusion in Septic Patients with Hypoalbuminemia: An International Retrospective Observational Study.Journal of clinical medicine · 2025Article
- The relationship between serum albumin level with burn severity and total body surface area before and after skin graft surgery in burn patients.Annals of burns and fire disasters · 2025Article
- Lactate to albumin ratio has limited prognostic value for complications in children under five with burn injuries.Scientific reports · 2025Article
- Red cell distribution width as a prognostic indicator in medical and surgical ICU patients.Frontiers in medicine · 2025Article
- Albumin: a comprehensive review and practical guideline for clinical use.European journal of clinical pharmacology · 2024Review
- The Role of Serum Albumin Level during Hospitalization as a Predictor of Complications and Mortality in Children with Burns.Medical journal of the Islamic Republic of Iran · 2023Article
- Investigation of red cell distribution width as a prognostic criterion in severe burns.International wound journal · 2022Article
- Predictors in major burn patients.Journal of the Chinese Medical Association : JCMA · 2020Article
- Reply to "Predictors in major burn patients".Journal of the Chinese Medical Association : JCMA · 2020Article
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9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBurns that affect ≥20% of the total body surface area (TBSA) trigger a major inflammatory response in addition to capillary leakage and loss of serum proteins including albumin. Persistent hypoalbuminemia is therefore common in major burn patients. The purpose of this study was to determine whether human albumin solutions can benefit major burn patients with persistent hypoalbuminemia.
methodsWe conducted a retrospective review of major burn patients with ≥20% of TBSA involved at Taipei Veterans General Hospital between January 2007 and December 2018. Thirty-eight patients were enrolled. Patient demographics, burn characteristics, fluid balance, laboratory results, and outcomes were recorded through chart review.
resultNo significant differences were found in the baseline characteristics of patients who received <25 mg/kg/%TBSA/day of human albumin solutions and those who received more than this amount. Renal replacement therapy, duration of mechanical ventilation, length of stay in the burn unit, and in-hospital mortality rate were not statistically different between the two groups. The serum C-reactive protein/albumin ratio was associated with in-hospital mortality (p = 0.036).
conclusionThe administration of large amounts of albumin supplements for the correction of prolonged hypoalbuminemia in major burn patients had no significant benefits on mortality.
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