Observational studyThe Pediatric infectious disease journal2020
Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children.
Observational study in The Pediatric infectious disease journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Pediatric and adult primary human airway epithelia exhibit similar rhinovirus C replication, innate responses, and expression of protein receptor.Microbiology spectrum · 2026Article
- The rhinovirus puzzle: Linking virus and host factors to childhood asthma.The Journal of allergy and clinical immunology · 2026Review
- Eighteen Years of Human Rhinovirus Surveillance in the Republic of Korea (2007-2024): Age- and Season-Specific Trends from a Single-Center Study with Public Health Implications.Pathogens (Basel, Switzerland) · 2025Article
- Clinical Significance of Rhinoviruses and Progress Toward Vaccination.Allergy, asthma & immunology research · 2025Review
- Association between cadherin-related family member 3 rs6967330-A and human rhinovirus-C induced wheezing in children.Virology journal · 2025Article
- Impact of Viral Lower Respiratory Tract Infection (LRTI) in Early Childhood (0-2 Years) on Lung Growth and Development and Lifelong Trajectories of Pulmonary Health: A National Institutes of Health (NIH) Workshop Summary.Pediatric pulmonology · 2025Review
- Association of rhinovirus and potentially pathogenic bacterial detections in the first 3 months of life with subsequent wheezing in childhood.Pediatric pulmonology · 2023Article
- Effects of COVID-19 and Social Distancing on Rhinovirus Infections and Asthma Exacerbations.Viruses · 2022Review
- Article
- Rapid syndromic testing for respiratory viral infections in children attending the emergency department during COVID-19 pandemic in Lille, France, 2021-2022.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022Article
- Human rhinoviruses prevailed among children in the setting of wearing face masks in Shanghai, 2020.BMC infectious diseases · 2022Article
- Article
- Rhinovirus spread in children during the COVID-19 pandemic despite social restrictions-A nationwide register study in Finland.Journal of medical virology · 2021Article
- Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.American journal of respiratory and critical care medicine · 2021Article
- A, B, and C Rhinoviruses: New Knowledge from an Impressive Consortium. A Step Forward for Rhinovirus Vaccine Efforts or a Step Back?American journal of respiratory and critical care medicine · 2021Article
- Detection of Virus-Related Sequences Associated With Potential Etiologies of Hepatitis in Liver Tissue Samples From Rats, Mice, Shrews, and Bats.Frontiers in microbiology · 2021Article
- Seasonal Coronaviruses and Other Neglected Respiratory Viruses: A Global Perspective and a Local Snapshot.Frontiers in public health · 2021Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRhinovirus is the most common virus causing respiratory tract illnesses in children. Rhinoviruses are classified into species A, B and C. We examined the associations between different rhinovirus species and respiratory illness severity.
methodsThis is a retrospective observational cohort study on confirmed rhinovirus infections in 134 children 3-23 months of age, who were enrolled in 2 prospective studies on bronchiolitis and acute otitis media, respectively, conducted simultaneously in Turku University Hospital, Turku, Finland, between September 2007 and December 2008.
resultsRhinovirus C is the most prevalent species in our study, and it was associated with severe wheezing and febrile illness. We also noted that history of atopic eczema was associated with wheezing.
conclusionsOur understanding of rhinovirus C as the most pathogenic rhinovirus species was fortified. Existing research supports the idea that atopic characteristics are associated with the severity of the rhinovirus C-induced illness.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.