Evidence map›Paper›PMID 31876394›Full record

ArticleMolecular genetics & genomic medicine2020

Forensic characteristics and genetic affinity analyses of Xinjiang Mongolian group using a novel six fluorescent dye-labeled typing system including 41 Y-STRs and 3 Y-InDels.

Yanfang Liu, Tingting Yu, Shuyan Mei, Xiaoye Jin, Qiong Lan, Yongsong Zhou, Yating Fang, Tong Xie, Jiabin Huang, Bofeng Zhu

RetractedAbstract readRetracted Publication
In one paragraph

Article in Molecular genetics & genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

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7citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yanfang LiuDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Tingting YuHEALTH GeneTech, Ningbo, China.
Shuyan MeiDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Xiaoye JinKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
Qiong LanDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Yongsong ZhouDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Yating FangDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Tong XieDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Jiabin HuangHEALTH GeneTech, Ningbo, China.
Bofeng ZhuDepartment of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China.ORCID 0000-0002-9038-2342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundY-chromosomal genetic marker haplotypes of individuals can define the paternal kinship or genealogies to which they belong and further provide clues for forensic individual identifications. Studying the genetic structure of the Mongolian group will help to bring to light the Mongolian ethnic origin, and explicate the genetic affinities among the studied and compared populations. Some forensic scientists have studied the genetic background of the Mongolian group based on different molecular genetic markers. These studies were of very great reference significance for the Mongolian group genetic research, whereas the investigation of Y-STR haplotype data in the Xinjiang Mongolian group is still insufficient.

methodsGenetic characteristics of 182 unrelated healthy male Mongolian individuals were revealed by 41 Y-chromosomal short tandem repeat and 3 insertion/deletion molecular genetic markers. Furthermore, analyses of molecular variance programs, multi-dimensional scaling plots, and phylogenetic tree reconstructions were operated to explore the genetic relationships of the Xinjiang Mongolian group with comparative 23 populations from China and 33 populations from worldwide nations.

resultsThe genetic diversity values ranged from 0.0641 (rs771783753) to 0.9502 (DYF387S1). A total of 165 distinct haplotypes were identified, of which 150 (90.91%) were unique. The discrimination capacity, match probability, and haplotype diversity of 44 loci were 0.9066, 0.0067, and 0.9988, respectively. Additionally, the Mongolian group had the most intimate relationship with Gansu Dongxiang (R

conclusionsConsequently, the 44 loci could be well applied in forensic applications of the Mongolian group. The haplotypes available in here made new contributions to the existing population genetic information and would be of great value in population studies.

Indexed as

Polymorphism, GeneticAsian PeopleChinaChromosomes, Human, YForensic GeneticsGenotyping TechniquesHaplotypesHumansINDEL MutationMaleMicrosatellite RepeatsPedigreePhylogenyforensic geneticsMongolian ethnic minoritypopulation genetic analysisY-chromosome STR

Identifiers

PMID31876394
PMCPMC7005640

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