ArticlePhysiological reports2019
Echocardiographic evaluations of right ventriculo-arterial coupling in experimental and clinical pulmonary hypertension.
Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Echocardiographic correlates of pressure-volume-derived indices: Advancing intraoperative assessment of right ventricular function.JTCVS open · 2026Article
- Article
- Physical exercise for pulmonary arterial hypertension diagnosis and therapy.International journal of cardiology. Congenital heart disease · 2025Review
- Impairment in Right Ventricular-Pulmonary Arterial Coupling in Overweight and Obesity.Journal of clinical medicine · 2024Article
- Cardiac magnetic resonance imaging in repaired tetralogy of Fallot: A longitudinal midterm follow-up study.PloS one · 2024Article
- Novel Echocardiographic Measurements of Right Ventricular-Pulmonary Artery Coupling in Predicting the Prognosis of Precapillary Pulmonary Hypertension.Journal of personalized medicine · 2023Article
- Impact of sternotomy and pericardiotomy on cardiopulmonary haemodynamics in a large animal model.Experimental physiology · 2023Article
- Adaptive versus maladaptive right ventricular remodelling.ESC heart failure · 2023Review
- Pulsatile pulmonary artery pressure in a large animal model of chronic thromboembolic pulmonary hypertension: Similarities and differences with human data.Pulmonary circulation · 2022Article
- Right Ventricular-Pulmonary Arterial Coupling in Repaired Tetralogy of Fallot.Pediatric cardiology · 2022Article
- Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?Journal of clinical medicine · 2021Review
- Echocardiographic evaluation of right ventricular-arterial coupling in pulmonary hypertension.American journal of cardiovascular disease · 2020Review
- Echocardiographic evaluations of right ventriculo-arterial coupling in experimental and clinical pulmonary hypertension.Physiological reports · 2019Article
- Hemodynamic trajectories and outcomes in patients with pulmonary arterial hypertension.Pulmonary circulationArticle
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Authors and funding
7 authors.
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Abstract
backgroundTricuspid annular systolic excursion (TAPSE) or velocities (s') and right ventricular (RV) end-systolic dimensions are predictors of outcome in patients with pulmonary hypertension (PH). We explored the value of combining peak s' and RV end-systolic area index (RVESAi) as a surrogate of RV-pulmonary artery (RV-PA) coupling in a large animal of precapillary PH as well as clinically.
methodThe first experimental group included four control and four piglets with thromboembolic disease. RV-PA coupling was assessed by ventricular to arterial elastance ratio (Ees/Ea) at baseline, after esmolol and dobutamine administration. Echocardiographic metrics included s', TAPSE, fractional area change (RVFAC), and RVESAi. The findings were validated in six piglets with severe PH. Clinical cohorts were stable outpatients (n = 141) and acutely decompensated pulmonary arterial hypertension (n = 48).
resultsIn the first experimental group, the best linear correlates of Ees/Ea were s' (R
conclusionRV s'/RVESAi index represents a reasonable bedside-usable surrogate of RV-PA coupling and of its acute variations in PH. Its incremental prognostic value over end-systolic dimension alone remains to be proven.
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