Evidence map›Paper›PMID 31876091›Full record

ArticleEnvironmental microbiology2020

Colonies of the fungus Aspergillus niger are highly differentiated to adapt to local carbon source variation.

Paul Daly, Mao Peng, Hugh D Mitchell, Young-Mo Kim, Charles Ansong, Heather Brewer, Peter de Gijsel, Mary S Lipton, Lye Meng Markillie, Carrie D Nicora and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Sugar Metabolic Model ofJournal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Paul DalyFungal Physiology, Westerdijk Fungal Biodiversity Institute & Fungal Molecular Physiology, Utrecht University, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.ORCID 0000-0002-6863-2536
Mao PengFungal Physiology, Westerdijk Fungal Biodiversity Institute & Fungal Molecular Physiology, Utrecht University, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
Hugh D MitchellBiological Sciences Divisions, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Young-Mo KimBiological Sciences Divisions, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Charles AnsongBiological Sciences Divisions, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Heather BrewerEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Peter de GijselLaboratory of Food Chemistry, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
Mary S LiptonEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Lye Meng MarkillieBiological Sciences Divisions, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Carrie D NicoraBiological Sciences Divisions, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Galya OrrEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Ad WiebengaFungal Physiology, Westerdijk Fungal Biodiversity Institute & Fungal Molecular Physiology, Utrecht University, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
Kristiina S HildénDepartment of Microbiology, University of Helsinki, Viikinkaari 9, 00790 Helsinki, Finland.
Mirjam A KabelLaboratory of Food Chemistry, Wageningen University, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
Scott E BakerEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Miia R MäkeläDepartment of Microbiology, University of Helsinki, Viikinkaari 9, 00790 Helsinki, Finland.ORCID 0000-0003-0771-2329
Ronald P de VriesFungal Physiology, Westerdijk Fungal Biodiversity Institute & Fungal Molecular Physiology, Utrecht University, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.ORCID 0000-0002-4363-1123

Funding

Netherlands Scientific Organization NWO 824.15.023
6 · The paper itself

Abstract

Saprobic fungi, such as Aspergillus niger, grow as colonies consisting of a network of branching and fusing hyphae that are often considered to be relatively uniform entities in which nutrients can freely move through the hyphae. In nature, different parts of a colony are often exposed to different nutrients. We have investigated, using a multi-omics approach, adaptation of A. niger colonies to spatially separated and compositionally different plant biomass substrates. This demonstrated a high level of intra-colony differentiation, which closely matched the locally available substrate. The part of the colony exposed to pectin-rich sugar beet pulp and to xylan-rich wheat bran showed high pectinolytic and high xylanolytic transcript and protein levels respectively. This study therefore exemplifies the high ability of fungal colonies to differentiate and adapt to local conditions, ensuring efficient use of the available nutrients, rather than maintaining a uniform physiology throughout the colony.

Indexed as

Adaptation, PhysiologicalAspergillus nigerBiomassCarbonHyphaePectinsCarbonPectins

Identifiers

PMID31876091
PMCPMC7065180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.