ArticlePhysiological reports2019
In vitro evidence of decompression bubble dynamics and gas exchange on the luminal aspect of blood vessels: Implications for size distribution of venous bubbles.
Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Circulating Bubbles in Decompression Sickness: Pathophysiology and Experimental Models.Biomolecules · 2026Review
- Taravana syndrome and posterior reversible encephalopathy syndrome: a microbubble hypothesis for neurological accidents in breath-hold divers.Frontiers in physiology · 2024Article
- Decompression Illness in Repetitive Breath-Hold Diving: Why Ischemic Lesions Involve the Brain?Frontiers in physiology · 2021Review
- In vitro evidence of decompression bubble dynamics and gas exchange on the luminal aspect of blood vessels: Implications for size distribution of venous bubbles.Physiological reports · 2019Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
We found that lung surfactant leaks into the bloodstream, settling on the luminal aspect of blood vessels to create active hydrophobic spots (AHS). Nanobubbles formed by dissolved gas at these AHS are most probably the precursors of gas micronuclei and decompression bubbles. Sheep blood vessels stretched on microscope slides, and exposed under saline to hyperbaric pressure, were photographed following decompression. Photographs of an AHS from a pulmonary vein, containing large numbers of bubbles, were selected in 1-min sequences over a period of 7 min, starting 18 min after decompression from 1,013 kPa. This showed bubble detachment, coalescence and expansion, as well as competition for dissolved gas between bubbles. There was greater expansion of peripheral than of central bubbles. We suggest that the dynamics of decompression bubbles on the surface of the blood vessel may be the closest approximation to true decompression physiology, and as such can be used to assess and calibrate models of decompression bubbles. We further discuss the implications for bubble size in the venous circulation.
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Registered trials
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