Evidence map›Paper›PMID 31876049›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Chirality-Driven Transportation and Oxidation Prevention by Chiral Selenium Nanoparticles.

Yanyu Huang, Yuanting Fu, Mengting Li, Dawei Jiang, Christopher J Kutyreff, Jonathan W Engle, Xiaoli Lan, Weibo Cai, Tianfeng Chen

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 120 citations in OpenAlex.

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  13. A mini review on selenium quantum dots: synthesis and biomedical applications.Frontiers in bioengineering and biotechnology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yanyu HuangDepartment of Chemistry, Jinan University, Guangzhou, 510632, China.
Yuanting FuDepartment of Chemistry, Jinan University, Guangzhou, 510632, China.
Mengting LiDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China.
Dawei JiangDepartment of Radiology, Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705-2275, USA.ORCID 0000-0002-4072-0075
Christopher J KutyreffDepartment of Radiology, Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705-2275, USA.
Jonathan W EngleDepartment of Radiology, Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705-2275, USA.
Xiaoli LanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China.
Weibo CaiDepartment of Radiology, Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705-2275, USA.ORCID 0000-0003-4641-0833
Tianfeng ChenDepartment of Chemistry, Jinan University, Guangzhou, 510632, China.
University of Wisconsin–Madison · USJinan University · CNWuhan Union Hospital · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

The chirality of nanoparticles directly influences their transport and biological effects under physiological conditions, but the details of this phenomenon have rarely been explored. Herein, chiral GSH-anchored selenium nanoparticles (G@SeNPs) are fabricated to investigate the effect of their chirality on their transport and antioxidant activity. G@SeNPs modified with different enantiomers show opposite handedness with a tunable circular dichroism signal. Noninvasive positron emission tomography imaging clearly reveals that

Indexed as

AnimalsAntioxidantsApoptosisBiological TransportCell AdhesionContrast MediaCopper RadioisotopesGlutathioneHumansMass SpectrometryMiceNanoparticlesOxidation-ReductionOxidative StressPositron-Emission TomographyRatsAntioxidantsContrast MediaCopper RadioisotopesGlutathioneSeleniumchiralitydrug deliverynanodrugsselenium nanoparticles

Identifiers

PMID31876049
PMCPMC7123465
OpenAlexW2998314570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.