SynthesisThe British journal of surgery2020
Recurrence of idiopathic acute pancreatitis after cholecystectomy: systematic review and meta-analysis.
Synthesis in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06124989 (A Novel Machine Learning Model for the Prediction of Relapse of Acute Biliary Pancreatitis), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Novel Machine Learning Model for the Prediction of Relapse of Acute Biliary Pancreatitis (Machine learnINg for the rElapse Risk eValuation in Acute Biliary Pancreatitis - MINERVA)
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- A systematic review of the predictive factors for the recurrence of acute pancreatitis.World journal of emergency surgery : WJES · 2025Pooled it
- American College of Gastroenterology Guidelines: Management of Acute Pancreatitis.The American journal of gastroenterology · 2024Guideline
- Pooled it
- Leaving No Stone Unturned - Update on the Current Approach to Diagnosing and Treatment of Idiopathic Acute Pancreatitis.Digestive diseases and sciences · 2026Article
- Management of Idiopathic Acute Pancreatitis in Europe: An International Pancreas2000 Survey.Digestive diseases and sciences · 2026Article
- Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management.Journal of clinical medicine · 2026Review
- Microlithiasis-Induced Acute Papillitis Triggers Acute Pancreatitis: Where Do We Go From Here?United European gastroenterology journal · 2026Article
- Self-management barriers in recurrent acute pancreatitis: a qualitative study from the health belief model perspective.Frontiers in public health · 2026Article
- Endoscopic Management of Recurrent Acute Pancreatitis.Journal of clinical medicine · 2025Review
- Machine learning for the rElapse risk eValuation in acute biliary pancreatitis: The deep learning MINERVA study protocol.World journal of emergency surgery : WJES · 2025Article
- A Nomogram for Predicting the Transition From Recurrent Acute Pancreatitis to Chronic Pancreatitis.Pancreas · 2025Article
- Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Review
- Idiopathic acute pancreatitis (IAP)-a review of the literature and algorithm proposed for the diagnostic work-up of IAP.Translational gastroenterology and hepatology · 2024Review
- Comparison of the effects of ampulla-guided realignment and conventional gallbladder triangle anatomy in difficult laparoscopic cholecystectomy.Langenbeck's archives of surgery · 2023Article
- Prospective multicentre study of indications for surgery in patients with idiopathic acute pancreatitis following endoscopic ultrasonography (PICUS).The British journal of surgery · 2023Article
- Natural Course of Common Bile Duct Microlithiasis.Digestive diseases and sciences · 2023Article
- What has changed? The impact of the COVID-19 pandemic on the management of acute biliary pancreatitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Machine learning-based decision tool for selecting patients with idiopathic acute pancreatitis for endosonography to exclude a biliary aetiology.World journal of gastroenterology · 2023Article
- Acute Recurrent Pancreatitis With Exclusion of Biliary Causes in a Young Female Patient.Cureus · 2023Article
- High Clinical and Genetic Similarity Between Chronic Pancreatitis Associated With Light-to-Moderate Alcohol Consumption and Classical Alcoholic Chronic Pancreatitis.Gastro hep advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOccult biliary disease has been suggested as a frequent underlying cause of idiopathic acute pancreatitis (IAP). Cholecystectomy has been proposed as a strategy to prevent recurrent IAP. The aim of this systematic review was to determine the efficacy of cholecystectomy in reducing the risk of recurrent IAP.
methodsPubMed, Embase and Cochrane Library databases were searched systematically for studies including patients with IAP treated by cholecystectomy, with data on recurrence of pancreatitis. Studies published before 1980 or including chronic pancreatitis and case reports were excluded. The primary outcome was recurrence rate. Quality was assessed using the Newcastle-Ottawa Scale. Meta-analyses were undertaken to calculate risk ratios using a random-effects model with the inverse-variance method.
resultsOverall, ten studies were included, of which nine were used in pooled analyses. The study population consisted of 524 patients with 126 cholecystectomies. Of these 524 patients, 154 (29·4 (95 per cent c.i. 25·5 to 33·3) per cent) had recurrent disease. The recurrence rate was significantly lower after cholecystectomy than after conservative management (14 of 126 (11·1 per cent) versus 140 of 398 (35·2 per cent); risk ratio 0·44, 95 per cent c.i. 0·27 to 0·71). Even in patients in whom IAP was diagnosed after more extensive diagnostic testing, including endoscopic ultrasonography or magnetic resonance cholangiopancreatography, the recurrence rate appeared to be lower after cholecystectomy (4 of 36 (11 per cent) versus 42 of 108 (38·9 per cent); risk ratio 0·41, 0·16 to 1·07).
conclusionCholecystectomy after an episode of IAP reduces the risk of recurrent pancreatitis. This implies that current diagnostics are insufficient to exclude a biliary cause.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.