Evidence map›Paper›PMID 31875937›Full record

ArticleClinical and experimental nephrology2020

Blood pressure control in chronic kidney disease according to underlying renal disease: the Fukushima CKD cohort.

Aya Nakajima, Kenichi Tanaka, Hirotaka Saito, Tsuyoshi Iwasaki, Akira Oda, Makoto Kanno, Michio Shimabukuro, Koichi Asahi, Tsuyoshi Watanabe, Junichiro James Kazama

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Article in Clinical and experimental nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aya NakajimaDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Kenichi TanakaDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan. kennichi@fmu.ac.jp.ORCID http://orcid.org/0000-0003-4655-9355
Hirotaka SaitoDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Tsuyoshi IwasakiDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Akira OdaDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Makoto KannoDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Michio ShimabukuroDepartment of Diabetes, Endocrinology and Metabolism, Fukushima Medical University, Fukushima, Japan.
Koichi AsahiDepartment of Nephrology and Hypertension, Iwate Medical University, Morioka, Japan.
Tsuyoshi WatanabeFukushima Rosai Hospital, Iwaki, Japan.
Junichiro James KazamaDepartment of Nephrology and Hypertension, Fukushima Medical University, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Fukushima Medical University · JPIwate Medical University · JPJapan Organization of Occupational Health and Safety · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequate blood pressure control is one of the important causes of chronic kidney disease (CKD), but only a limited number of reports have examined blood pressure control in Japanese patients with pre-dialysis CKD. Differences in blood pressure control due to underlying renal disease in pre-dialysis patients with CKD were investigated in the present study using the baseline data of the Fukushima CKD cohort study.

methodsThe study involved 1351 CKD patients, classified by underlying disease of primary renal disease, hypertensive nephropathy, diabetic nephropathy, other nephropathies, or unknown. Target blood pressure of CKD patients was defined as < 130/80 mmHg in patients under 75 years old with diabetes and/or proteinuria, and < 140/90 mmHg in other patients.

resultsThe achievement rate of target systolic blood pressure was lower in the diabetic and hypertensive nephropathy groups than in the primary renal disease group (33.3%, 46.0% vs. 68.1%, p < 0.001). However, the number of antihypertensive medications increased in the diabetic and hypertensive nephropathy groups compared to the primary renal disease group (2.16, 2.04 vs. 1.55, p < 0.001). Inadequate blood pressure control was independently related to the underlying renal disease, with a significant difference between diabetic nephropathy and primary renal disease (odds ratio 3.19; 95% confidence interval, 2.16-4.69; p < 0.001).

conclusionThis study showed that blood pressure control differs by the underlying renal disease. Blood pressure control was poor especially in diabetic nephropathy despite multidrug combination antihypertensive treatment. It is necessary to verify whether strict blood pressure control improves patients' prognosis in diabetic nephropathy.

Indexed as

Blood PressureAgedAntihypertensive AgentsCross-Sectional StudiesDiabetic NephropathiesFemaleGlomerulonephritisHumansHypertensionHypertension, RenalJapanMaleMiddle AgedNephritisProspective StudiesRenal Insufficiency, ChronicAntihypertensive AgentsBlood pressure controlChronic kidney disease (CKD)Diabetic nephropathyUnderlying renal disease

Identifiers

PMID31875937
OpenAlexW2998621217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.