Evidence map›Paper›PMID 31875924›Full record

ArticleMolecular neurobiology2020

Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene.

Kinga Gawel, Waldemar A Turski, Wietske van der Ent, Benan J Mathai, Karolina J Kirstein-Smardzewska, Anne Simonsen, Camila V Esguerra

Open access · hybridAbstract read
In one paragraph

Article in Molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
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  4. Article
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  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. P/Q type (CaMolecular neurobiology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Significance of Astragaloside IV from the Roots ofInternational journal of molecular sciences · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kinga GawelChemical Neuroscience Group, Centre for Molecular Medicine Norway, Faculty of Medicine, University of Oslo, Gaustadalléen 21, Forskningsparken, 0349, Oslo, Norway.ORCID http://orcid.org/0000-0001-8857-847X
Waldemar A TurskiDepartment of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego St. 8b, 20-090, Lublin, Poland.ORCID http://orcid.org/0000-0002-5805-5106
Wietske van der EntChemical Neuroscience Group, Centre for Molecular Medicine Norway, Faculty of Medicine, University of Oslo, Gaustadalléen 21, Forskningsparken, 0349, Oslo, Norway.ORCID http://orcid.org/0000-0003-2165-9624
Benan J MathaiFaculty of Medicine, Institute of Basic Medical Sciences and Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, University of Oslo, 1112 Blindern, 0317, Oslo, Norway.ORCID http://orcid.org/0000-0002-9549-2073
Karolina J Kirstein-SmardzewskaChemical Neuroscience Group, Centre for Molecular Medicine Norway, Faculty of Medicine, University of Oslo, Gaustadalléen 21, Forskningsparken, 0349, Oslo, Norway.
Anne SimonsenFaculty of Medicine, Institute of Basic Medical Sciences and Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, University of Oslo, 1112 Blindern, 0317, Oslo, Norway.ORCID http://orcid.org/0000-0003-4711-7057
Camila V EsguerraChemical Neuroscience Group, Centre for Molecular Medicine Norway, Faculty of Medicine, University of Oslo, Gaustadalléen 21, Forskningsparken, 0349, Oslo, Norway. c.v.esguerra@ncmm.uio.no.ORCID http://orcid.org/0000-0002-2271-8094
University of Oslo · NOMedical University of Lublin · PL

Funding

H2020 Marie Skłodowska-Curie Actions 798703-GEMZ-H2020-MSCA-IF-2017Ministerstwo Nauki i Szkolnictwa Wyższego 1649/1/MOB/V/17/2018/0Research Council of Norway 262652Research Council of Norway FRIPRO grant (project number 221831)Universitetet i Oslo -
6 · The paper itself

Abstract

The CACNA1A gene encodes the pore-forming α1 subunit of voltage-gated P/Q type Ca

Indexed as

Gene Knockdown TechniquesAnimalsBehavior, AnimalBrainCalcium ChannelsCalcium Channels, N-TypeElectroencephalographyGene Expression Regulation, DevelopmentalHumansLarvaMorpholinosMotor ActivityPhenotypeTouchZebrafishZebrafish Proteinscacna1aa protein, zebrafishCalcium ChannelsCalcium Channels, N-TypeMorpholinosZebrafish ProteinsAntiseizure drugsCACNA1A geneEpilepsyLoss of functionTouch responseZebrafish

Identifiers

PMID31875924
PMCPMC7118054
OpenAlexW2997366554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.