Evidence map›Paper›PMID 31875760›Full record

ArticlePharmaceutical biology2020

Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway.

Wen-Qiang Cao, Xiao-Qian Zhai, Ji-Wei Ma, Xue-Qi Fu, Bai-Song Zhao, Pu Zhang, Xiao-Yan Fu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
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  6. Study on the mechanism of Shenmai injection in the treatment of sepsis.Journal of cellular and molecular medicine · 2024
    Article
  7. Unlocking the mechanistic potential ofJournal of traditional and complementary medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wen-Qiang CaoSchool of Life Sciences, Jilin University, Changchun, China.
Xiao-Qian ZhaiDepartment of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Taian, China.
Ji-Wei MaDepartment of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Xue-Qi FuSchool of Life Sciences, Jilin University, Changchun, China.
Bai-Song ZhaoDepartment of Biotechnology, Zhuhai Hopegenes Medical & Phamaceutical Institute, Zhuhai, China.
Pu ZhangDepartment of Cardiology, The Central Hospital of Taian, Taian, China.
Xiao-Yan FuSchool of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China.ORCID http://orcid.org/0000-0002-2939-7748
Jilin University · CNTaian City Central Hospital · CNAffiliated Hospital of Taishan Medical University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsApoptosisCamphanesCell Line, TumorCell SurvivalCisplatinDNA DamageDose-Response Relationship, DrugDrug Resistance, NeoplasmGliomaHumansOxidative StressPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAntineoplastic AgentsCamphanesCisplatinisoborneolPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAktChemo-sensitizationDNA damageERKp53reactive oxygen species

Identifiers

PMID31875760
PMCPMC6970185
OpenAlexW2998004290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.