Evidence map›Paper›PMID 31875721›Full record

ArticleConnective tissue research

The age-dependent effect of high-dose X-ray radiation on NFκB signaling, structure, and mechanical behavior of the intervertebral disc.

Jennifer W Liu, Sytse Piersma, Simon Y Tang

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Connective tissue research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer W LiuDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Sytse PiersmaDivision of Rheumatology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Simon Y TangDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.ORCID 0000-0002-5570-3921
Washington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI VEIS, DEBORAH J · 2009 to 2018
$5.7M
The role of physiologic and pathologic AGEs on RAGE signaling in IVD degenerationR01AR074441 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2019 to 2024
$2.1M
Tissue Level Deformations of the Loaded Spine in Humans with Low Back PainK01AR069116 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2016 to 2019
$489k
Effects of Ages and Rage on IVD Degeneration And InflammationR21AR069804 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2017 to 2018
$369k
NCATS NIH HHS UL1 TR002345NIAMS NIH HHS K01 AR069116NIAMS NIH HHS P30 AR057235NIAMS NIH HHS P30 AR074992NIAMS NIH HHS R01 AR074441NIAMS NIH HHS R21 AR069804
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsFemaleIntervertebral DiscMaleMiceMice, TransgenicMyeloid Differentiation Factor 88NF-kappa BSignal TransductionX-RaysMyd88 protein, mouseMyeloid Differentiation Factor 88NF-kappa BdegenerationInflammationIntervertebral discIonizing radiationNFκBorgan culture

Identifiers

PMID31875721
PMCPMC7190425
OpenAlexW2996822871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.