Evidence map›Paper›PMID 31875700›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2020

How to Measure Arterial Stiffness in Humans.

Patrick Segers, Ernst R Rietzschel, Julio A Chirinos

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06836622 (Correlation Between the Values of Carotid-Femoral, Oscillometric and Estimated Pulse Wave Velocity), which is not on this map. Cited by 123 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 5 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06836622 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Correlation Between the Values of Carotid-Femoral, Oscillometric and Estimated Pulse Wave Velocity

TypeobservationalSponsorHospital de BaseRan2026 to 2027Enrolled350ConditionsHypertension, Arterial Stiffness, Pulse Wave Analysis, Pulse Wave Velocity
3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 5 syntheses or guidelines pooled it, 225 citations in OpenAlex.

  1. Pooled it
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  6. Trial
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  11. Cardiovascular frailty - an emerging frailty phenotype.Journal of human hypertension · 2026
    Review
  12. Effects of sympathomodulation on pulse wave properties in heart failure with preserved ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  13. Review
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  19. Observational
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63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Patrick SegersFrom the Biofluid, Tissue, and Solid Mechanics for Medical Applications, IBiTech Ghent (P.S.), University of Ghent, Belgium.
Ernst R RietzschelDepartments of Cardiology, Biobanking, and Cardiovascular Epidemiology (E.R.R.), University of Ghent, Belgium.
Julio A ChirinosDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, PA (J.A.C.).
Ghent University · BEHospital of the University of Pennsylvania · US

Funding

Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)R01AG058969 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Timothy M. Hughes, YONGMEI LIU · 2018 to 2026
$33.4M
Understanding the relationship between obesity and tongue fat in humans and ratsP01HL094307 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MAISLIN, GREG · 2009 to 2020
$23.7M
VASCULAR EFFECTS OF DIETARY SALT IN HUMANS WITH SALT-RESISTANT BPR01HL104106 · NHLBI · UNIVERSITY OF DELAWARE · PI EDWARDS, DAVID G, FARQUHAR, WILLIAM B · 2011 to 2021
$4.5M
Efficacy of Potassium Nitrate in Heart Failure with Preserved Ejection FractionR01HL121510 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHIRINOS MEDINA, JULIO ALONSO · 2015 to 2019
$3.1M
Genetic determinants of thoracic aortic stiffness and remodelingK24AG070459 · NIA · UNIVERSITY OF PENNSYLVANIA · PI CHIRINOS MEDINA, JULIO ALONSO · 2021 to 2025
$975k
Cardiovascular Risk after Preeclampsia - The CRISP studyR56HL136730 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LEVINE, LISA DANIELLE · 2018 to 2018
$740k
Developing Oral LT3 Therapy for Heart FailureR61HL146390 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, ANNE R, CAPPOLA, THOMAS P. · 2019 to 2019
$403k
Understanding Racial Differences in Vascular Function and Ventricular-Vascular Coupling in Heart Failure with Preserved Ejection FractionR03HL146874 · NHLBI · EMORY UNIVERSITY · PI MORRIS, ALANNA AMYRE · 2019 to 2020
$156k
NHLBI NIH HHS P01 HL094307NHLBI NIH HHS R01 HL104106NHLBI NIH HHS R01 HL121510NHLBI NIH HHS R03 HL146874NHLBI NIH HHS R56 HL136730NHLBI NIH HHS R61 HL146390NIA NIH HHS K24 AG070459NIA NIH HHS R01 AG058969
6 · The paper itself

Abstract

Despite the wide recognition of larger artery stiffness as a highly clinically relevant and independent prognostic biomarker, it has yet be incorporated into routine clinical practice and to take a more prominent position in clinical guidelines. An important reason may be the plethora of methods and devices claiming to measure arterial stiffness in humans. This brief review provides a concise overview of methods in use, indicating strengths and weaknesses. We classified and graded methods, highly weighing their scrutiny and purity in quantifying arterial stiffness, rather than focusing on their ease of application or the level at which methods have demonstrated their prognostic and diagnostic potential.

Indexed as

Blood Pressure DeterminationElasticity Imaging TechniquesPulse Wave AnalysisVascular StiffnessArterial PressureArteriesCardiovascular DiseasesElasticityHumansPredictive Value of TestsPrognosisReproducibility of ResultsRisk AssessmentRisk FactorsSeverity of Illness Indexaortaarteriolescollagenhomeostasisprognosis

Identifiers

PMID31875700
PMCPMC7180118
OpenAlexW2998385609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.