ArticleCell reports2019
Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease.
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Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
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Who cites it
31 citing papers in PubMed, 44 citations in OpenAlex.
- Innate Lymphoid Cells Activation and Transcriptomic Changes in Response to Human Dengue Infection.Frontiers in immunology · 2021Trial
- Bulk transcriptomics of peripheral blood mononuclear cells delineates systems-level immune dysregulation in pediatric dengue infection.NPJ systems biology and applications · 2026Article
- Proteomic signals are not equal clinical phenotypes: redefining evidence standards in arbovirus-SARS-CoV-2 cross-reactivity.Frontiers in immunology · 2026Review
- T Cell Responses During Dengue Infection.Current topics in microbiology and immunology · 2026Review
- Distinct features of a peripheral T helper subset that drives the B cell response in dengue virus infection.Cell reports · 2025Article
- Characterization of dengue patients in Vietnam: Clinical, virological, and IL-10 profiles during 2021- 2022 outbreaks.PLoS neglected tropical diseases · 2025Article
- Frequency of dengue virus-specific T cells is related to infection outcome in endemic settings.JCI insight · 2025Article
- NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics.The Journal of clinical investigation · 2024Article
- Article
- A causal multiomics study discriminates the early immune features of Ad5-vectored Ebola vaccine recipients.Innovation (Cambridge (Mass.)) · 2024Article
- Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans.Cell reports · 2024Article
- Early cellular and molecular signatures correlate with severity of West Nile virus infection.iScience · 2023Article
- An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications.Virulence · 2023Review
- A Prototype-Pathogen Approach for the Development of Flavivirus Countermeasures.The Journal of infectious diseases · 2023Review
- Prediction of human protein interactome of dengue virus non-structural protein 5 (NS5) and its downstream immunological implications.3 Biotech · 2023Article
- Analysis of gene expression profile for identification of novel gene signatures during dengue infection.Infectious medicine · 2023Article
- Type I regulatory T cells in malaria: of mice and men.The Journal of clinical investigation · 2023Article
- IL-10-producing Th1 cells possess a distinct molecular signature in malariaThe Journal of clinical investigation · 2023Article
- Longitudinal proteomic profiling of the inflammatory response in dengue patients.PLoS neglected tropical diseases · 2023Article
- Article
Corrections and comments
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Authors and funding
19 authors at 7 institutions in 3 countries.
Yuan TianDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: ytian@lji.org.
Grégory SeumoisDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Luzia M De-Oliveira-PintoDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Jose MateusDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Sara Herrera-de la MataDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Cheryl KimFlow Cytometry Core Facility, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Denise HinzFlow Cytometry Core Facility, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
N D Suraj GoonawardhanaDepartment of Paraclinical Sciences, General Sir John Kotelawala Defense University, Ratmalana 10390, Sri Lanka.
Aruna D de SilvaDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Department of Paraclinical Sciences, General Sir John Kotelawala Defense University, Ratmalana 10390, Sri Lanka.
Sunil PremawansaDepartment of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 00300, Sri Lanka.
Gayani PremawansaNorth Colombo Teaching Hospital, Ragama 11010, Sri Lanka.
Ananda WijewickramaNational Institute of Infectious Diseases, Gothatuwa, Angoda 10620, Sri Lanka.
Angel BalmasedaLaboratorio Nacional de Virología, Centro Nacional de Diagnóstico y Referencia, Ministerio de Salud, Managua 16064, Nicaragua.
Alba GrifoniDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Pandurangan VijayanandDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.
Bjoern PetersDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Daniela WeiskopfDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
La Jolla Institute for Immunology · USUniversity of California, San Diego · USColombo North Teaching Hospital · LKGeneral Sir John Kotelawala Defence University · LKMinisterio de Salud · NIUniversity of California, Berkeley · USUniversity of Colombo · LK
Funding
Single-cell atlas of lung tissue-resident memory T cells reactive to upper and lower respiratory tract pathogensU19AI118626 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Alessandro Sette · 2015 to 2026
$36.7MT Cell Responses Following DENV Natural Infections and Live-Attenuated Dengue Virus VaccinationP01AI106695 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Aravinda M. DeSilva · 2015 to 2026
$34.1MCyTOF Mass CytometerS10OD018499 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2014 to 2014
$802kIllumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600kFACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514kNCRR NIH HHS S10 RR027366NIAID NIH HHS HHSN272200900042CNIAID NIH HHS P01 AI106695NIAID NIH HHS U19 AI118626NIH HHS S10 OD016262NIH HHS S10 OD018499
Abstract
Dengue virus (DENV) can cause diseases ranging from dengue fever (DF) to more severe dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Whether antiviral T cells contribute to the protection against or pathogenesis of severe disease is not well defined. Here, we identified antigen-specific IL-10
Indexed as
AdolescentAdultAntigens, CDCase-Control StudiesDengue VirusFemaleGene Expression RegulationGPI-Linked ProteinsHumansInterferon-gammaInterleukin-10Interleukin-21Interleukin-22InterleukinsMaleMiddle AgedAntigens, CDCCR1 protein, humanCD109 protein, humanGPI-Linked ProteinsIL10 protein, humanInterferon-gammaInterleukin-10Interleukin-21Interleukin-22InterleukinsNeoplasm ProteinsReceptors, CCR1acute dengueCD4 T cellCyTOFdengue feverdengue hemorrhagic feverdengue virusIFN-γIL-10RNA-seqtranscriptomics
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.