Evidence map›Paper›PMID 31875487›Full record

ArticleJournal of neurophysiology2020

Serotonergic control of GABAergic inhibition in the lateral amygdala.

Ryo Yamamoto, Takafumi Furuyama, Tokio Sugai, Munenori Ono, Denis Pare, Nobuo Kato

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Layer 5 Intratelencephalic Neurons in the Motor Cortex Stably Encode Skilled Movement.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ryo YamamotoDepartment of Physiology, Kanazawa Medical University, Ishikawa, Japan.
Takafumi FuruyamaDepartment of Physiology, Kanazawa Medical University, Ishikawa, Japan.
Tokio SugaiDepartment of Physiology, Kanazawa Medical University, Ishikawa, Japan.
Munenori OnoDepartment of Physiology, Kanazawa Medical University, Ishikawa, Japan.ORCID 0000-0001-9421-7021
Denis PareCenter for Molecular and Behavioral Neuroscience, Rutgers University-Newark, Newark, New Jersey.
Nobuo KatoDepartment of Physiology, Kanazawa Medical University, Ishikawa, Japan.
Kanazawa Medical University · JPRutgers, The State University of New Jersey · US

Funding

Closed-loop optogenetic control of gamma oscillations and emotional learningR01MH119854 · NIMH · RUTGERS THE STATE UNIV OF NJ NEWARK · PI PARE, DENIS · 2019 to 2023
$1.9M
NIMH NIH HHS R01 MH119854
6 · The paper itself

Abstract

Much evidence implicates the serotonergic regulation of the amygdala in anxiety. Thus the present study was undertaken to characterize the influence of serotonin (5-HT) on principal neurons (PNs) of the rat lateral amygdala (LA), using whole cell recordings in vitro. Because inhibition is a major determinant of PN activity, we focused on the control of GABAergic transmission by 5-HT. IPSCs were elicited by local electrical stimulation of LA in the presence of glutamate receptor antagonists. We found that 5-HT reduces GABA

Indexed as

AnimalsBasolateral Nuclear ComplexElectric StimulationFemalegamma-Aminobutyric AcidInhibitory Postsynaptic PotentialsMalePatch-Clamp TechniquesRatsRats, WistarReceptor, Serotonin, 5-HT1BReceptors, GABA-AReceptors, GABA-BSerotoningamma-Aminobutyric AcidReceptor, Serotonin, 5-HT1BReceptors, GABA-AReceptors, GABA-BSerotonin5-HT1B receptorGABAA receptorGABAB receptorlateral amygdalaserotonin

Identifiers

PMID31875487
PMCPMC7395475
OpenAlexW2997605727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.