Evidence map›Paper›PMID 31875190›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2019

Primary Spinal Epidural/Extramedullary Ewing Sarcoma in Young Female Patients.

Amanda N Fletcher, Joanne Abby M Marasigan, Stephen V Hiatt, John T Anderson, Eugenio M Taboada, Richard M Schwend

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Amanda N FletcherDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
Joanne Abby M MarasiganDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
Stephen V HiattDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
John T AndersonDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
Eugenio M TaboadaDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
Richard M SchwendDepartment of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina (Dr. Fletcher); Department of Orthopaedic Surgery, University of Missouri Kansas City School of Medicine, Kansas City, Missouri (Dr. Marasigan); the Department of Orthopaedic Surgery, Kansas City Bone and Joint Clinic, Kansas City, Missouri (Dr. Hiatt); the Department of Orthopaedic Surgery, Kansas City, Missouri (Dr. Anderson and Dr. Schwend), Children's Mercy Hospital, Kansas City; and the Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, Missouri (Dr. Taboada).
Duke Medical Center · USChildren's Mercy Hospital · USUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary spinal epidural/extramedullary ewing sarcoma (ES) is a rare extraosseous lesion. Extraosseous ES has a similar demographic as osseous ES, primarily affecting adolescents and young adults and male propensity. Reported 5-year survival is 0% to 37.5% for spinal extraosseous ES.

methodsTwo girls, 19 and 14 months old, presented with progressive lower extremity paraplegia and incontinence. Both had a compressive epidural/extramedullary mass without metastases and underwent decompression with multilevel laminectomy and tumor excision. Primary spinal epidural/extramedullary ES was diagnosed.

resultsCase 1 received 34 weeks of chemotherapy and radiation therapy, and case 2 received 14 cycles of chemotherapy and autologous stem cell rescue without radiation therapy. After more than 5- and 8-year follow-up, case 1 and case 2 are walking and disease-free, respectively.

conclusionThese cases are the youngest presentation reported for primary spinal epidural/extramedullary ES and suggest that toddlers have a better prognosis for survival than older children and adolescents.

Identifiers

PMID31875190
PMCPMC6903810
OpenAlexW2990777629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.