Evidence map›Paper›PMID 31875180›Full record

ArticleACS sensors2016

Nitric oxide permselectivity in electropolymerized films for sensing applications.

Micah D Brown, Mark H Schoenfisch

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  8. Mode of nitric oxide delivery affects antibacterial action.ACS biomaterials science & engineering · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Micah D BrownDepartment of Chemistry, University of North Carolina at Chapel Hill, CB 3290, Chapel Hill, NC 27599.
Mark H SchoenfischDepartment of Chemistry, University of North Carolina at Chapel Hill, CB 3290, Chapel Hill, NC 27599.
University of North Carolina at Chapel Hill · US

Funding

Microfluidic Nitric Oxide SensorR42AI112064 · NIAID · CLINICAL SENSORS, INC. · PI CAIRNS, BRUCE A, MCDUNN, JONATHAN EDWARD · 2017 to 2018
$1.4M
Nitric Oxide Microfluidic SensorR41AI112064 · NIAID · CLINICAL SENSORS, INC. · PI SCHOENFISCH, MARK H · 2014 to 2015
$600k
NIAID NIH HHS R41 AI112064NIAID NIH HHS R42 AI112064
6 · The paper itself

Abstract

The presence of biological interferents in physiological media necessitates chemical modification of the working electrode to facilitate accurate electrochemical measurement of nitric oxide (NO). In this study, we evaluated a series of self-terminating electropolymerized films prepared from one of three isomers of phenylenediamine (PD), phenol, eugenol, or 5-amino-1-naphthol (5A1N) to improve the NO selectivity of a platinum working electrode. The electrodeposition procedure for each monomer was individually optimized using cyclic voltammetry (CV) or constant potential amperometry (CPA). Cyclic voltammetry deposition parameters favoring slower film formation generally yielded films with improved selectivity for NO over nitrite and l-ascorbate. Nitric oxide sensors were fabricated and compared using the optimized deposition procedure for each monomer. Sensors prepared using poly-phenol and poly-5A1N film-modified platinum working electrodes demonstrated the most ideal analytical performance, with the former demonstrating the best selectivity. In simulated wound fluid, platinum electrodes modified with poly-5A1N films proved superior with respect to the NO sensitivity and detection limit.

Indexed as

5-amino-1-naphtholelectropolymerizationeugenolnitric oxidepermselectivityphenolphenylenediaminepolymer-modified electrode

Identifiers

PMID31875180
PMCPMC6929558
OpenAlexW2556873205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.