Evidence map›Paper›PMID 31875172›Full record

ArticleJournal of dentistry (Shiraz, Iran)2019

Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma.

Parviz Deyhimi, Mahmoud Reza Arefian, Parvin Mahzouni

Open access · greenAbstract read
In one paragraph

Article in Journal of dentistry (Shiraz, Iran), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Retroperitoneal spindle cell tumor: a case report.Journal of surgical case reports · 2023
    Article
  4. [Roles of interleukin-6/signal transduction and activator of transcription 3 pathway andZhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Parviz DeyhimiDept. of Oral and Maxillofacial Pathology, Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Mahmoud Reza ArefianPostgraduate Student Dept. of Oral and Maxillofacial Pathology, Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Parvin MahzouniDept. of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

statement of the problemThe biologic behavior and histopathological features of fibromatosis are intermediate between those of fibroma and fibrosarcoma. PURPOSE: The aim of the present study was to determine useful histopathologic and immunohistochemical characteristics for the differentiation of these lesions. MATERIALS AND

methodIn this cross-sectional descriptive study, 40 specimens comprising 20 fibrosarcoma and 20 fibromatosis biopsies were selected. The histopathologic characteristics of these lesions were identified and immunohistochemical staining for Ki67 and β-catenin markers was performed. Sections were examined by light microscopy and positively stained cells were counted. Results were analyzed by SPSS 20 using Chi-square test, Mann-whitney test, and t-test (

resultsStatistical significant differences were observed between fibromatosis and fibrosarcoma in terms of distribution frequency, mitotic rate, herringbone pattern, cellularity, overlapping of nuclei, mean Ki67 score, and atypia rate. The other features including age, gender, necrosis, clarity of nucleoli and mean β-catenin were not significantly different.

conclusionThe present findings suggest the mitotic figures, Ki67, herringbone pattern, cellularity, and atypia are useful to differentiate fibromatosis from fibrosarcoma.

Indexed as

FibromatosisFibrosarcomaHistopathologyKi-67β-catenin

Identifiers

PMID31875172
PMCPMC6890813
OpenAlexW2916572576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.