Article3 Biotech2020
Synthesis of nanobubbles for improved ultrasound tumor-imaging applications.
Article in 3 Biotech, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ultrasound-Responsive Nanobubbles for Combined siRNA-Cerium Oxide Nanoparticle Delivery to Bone Cells.Pharmaceutics · 2023Article
- FN3 linked nanobubbles as a targeted contrast agent for US imaging of cancer-associated human PD-L1.Journal of controlled release : official journal of the Controlled Release Society · 2022Article
- Concurrent visual and acoustic tracking of passive and active delivery of nanobubbles to tumors.Theranostics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present work showed the preparation of highly stable spherical nanobubbles using 3 mg/ml of soy lipid and 1% of Tween 80 as surfactant. The prepared nanobubbles were characterized using TEM and zeta-potential analyzer, which confirmed the formation of spherical nanobubbles with negative surface charge and high structural stability. The MTT cell viability studies confirmed that the fabricated nanobubbles were safe and nontoxic. Furthermore, the ultrasound imaging studies were performed to assess the improved imaging facility of the prepared nanobubbles. The in vitro studies exhibited that both the nanobubbles and SonoVue had a similar image enhancement capability. The in vivo studies revealed that nanobubbles exhibited an enhanced tumor intensity, which was stronger compared to that of Sono Vue. Therefore, the prepared nanobubbles could have potential for effective tumor imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.