Evidence map›Paper›PMID 31875162›Full record

ArticlePeerJ2019

Heterologous expression, purification and biochemical characterization of a glutamate racemase (MurI) from

Xiangzhu Wang, Chanchan Chen, Ting Shen, Jiangying Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiangzhu Wang *Department of Operative Dentistry and Endodotics, Xiangya School of Stomatology, Xiangya Stomatological Hospital, Central South University, Changsha, Hunan, China.
Chanchan Chen *Department of Stomatology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Ting ShenDepartment of Operative Dentistry and Endodotics, Xiangya School of Stomatology, Xiangya Stomatological Hospital, Central South University, Changsha, Hunan, China.
Jiangying ZhangDepartment of Operative Dentistry and Endodotics, Xiangya School of Stomatology, Xiangya Stomatological Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNShenzhen Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlutamate racemase (MurI) is a cofactor-independent enzyme that is essential to the bacterial peptidoglycan biosynthesis pathway and has therefore been considered an attractive target for the development of antimicrobial drugs. While in our previous study the essentiality of the

methodsStructure characterization prediction and multiple sequence alignment were performed by bioinformatic analysis. Recombinant His

resultsThe glutamate racemase gene from

conclusionThe findings of this study provide insight into the structure and biochemical traits of the glutamate racemase in

Indexed as

Affinity chromatographyEnzymatic reactionGlutamate racemaseMurIPeptidoglycan biosynthesisProkaryotic expressionStreptococcus mutans

Identifiers

PMID31875162
PMCPMC6927343
OpenAlexW2995737434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.