ReviewJournal of ophthalmic & vision research
Topical Tacrolimus as an adjunct to Conventional Therapy for Stromal Herpetic Keratitis: a Randomized Clinical Trial.
Review in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Alleviation of Allergic Rhinoconjunctivitis Symptoms in Participants Treated with a 0.005% Tacrolimus Eye-Drop Solution.Clinical ophthalmology (Auckland, N.Z.) · 2024Trial
- Beyond the surface: a comprehensive review of corneal endotheliitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Article
- Correlation analysis of the copy number of aqueous humor HSV DNA with anterior chamber reaction, topical steroid responsiveness and prognosis of endothelial herpes simplex keratitis.BMC ophthalmology · 2025Article
- Topical Use of Tacrolimus in Corneal and Ocular Surface Pathologies: A Systematic Review.Journal of clinical medicine · 2025Review
- Topical Tacrolimus in the Management of High-Risk Keratoplasty: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Clinical Effectiveness, Safety, and Compliance of Two Compounded Formulations of Tacrolimus Eye Drops: An Open-Label, Sequential Prospective Study.International journal of molecular sciences · 2024Article
- Herpes simplex keratitis: A brief clinical overview.World journal of virology · 2024Review
- Comparison of the effects of 0.05% topical cyclosporine A versus 0.1% topical cyclosporine A on recurrence and clinical parameters following pterygium surgery.Turkish journal of medical sciences · 2024Article
- Frequency and visual outcomes of herpes simplex keratitis in a Kuwaiti tertiary referral center.Medical hypothesis, discovery & innovation ophthalmology journal · 2023Article
- The epidemiological aspects of fungal keratitis in a population sample from Northern Iran: A cross-sectional study.Journal of family medicine and primary care · 2022Article
- Syphilitic interstitial keratitis treated with topical tacrolimus.American journal of ophthalmology case reports · 2021Article
- Advancement on Sustained Antiviral Ocular Drug Delivery for Herpes Simplex Virus Keratitis: Recent Update on Potential Investigation.Pharmaceutics · 2020Review
- Comparison of Pterygium Recurrence with and without Using Postsurgical Topical Cyclosporin A 0.05%: A Randomized Clinical Trial.Journal of current ophthalmologyArticle
- Clinical strategies to prevent recurrence of Herpes simplex and Herpes zoster following ocular surgery: A comprehensive review with practical guidelines.Survey of ophthalmologyReview
- Topical Calcineurin Inhibitors: Expanding Indications for Corneal and Ocular Surface Inflammation.Journal of ophthalmic & vision researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigates the effects of 0.05% topical tacrolimus as an adjunct therapy for patients with non-necrotizing herpetic stromal keratitis (HSK).
methodsPatients with non-necrotizing HSK, referred to the Cornea Clinic at Hospital in Rasht, Iran, between September 2016 and February 2018, were randomly assigned to two groups. The case group (
resultsThe mean age of the patients was 46.2
conclusionThe addition of 0.05% topical tacrolimus enhances visual acuity and reduces corneal inflammation, neovascularization, and scarring; thus, it can used as an appropriate adjunct treatment for patients with HSK.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.