Evidence map›Paper›PMID 31874891›Full record

ArticleBMJ open2019

Cluster randomised controlled trial to determine the effect of peer delivery HIV self-testing to support linkage to HIV prevention among young women in rural KwaZulu-Natal, South Africa: a study protocol.

Oluwafemi Atanda Adeagbo, Nondumiso Mthiyane, Carina Herbst, Paul Mee, Melissa Neuman, Jaco Dreyer, Natsayi Chimbindi, Theresa Smit, Nonhlanhla Okesola, Cheryl Johnson and 5 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03751826 (Peer Delivery of HIV Self-Screening to Support Linkage to HIV Prevention in Rural KwaZulu-Natal, South Africa), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03751826 naunknown statusnot on this map

Peer Delivery of HIV Self-Screening to Support Linkage to HIV Prevention in Rural KwaZulu-Natal, South Africa: A Cluster Randomized Control Trial

TypeinterventionalSponsorUniversity College, LondonRan2019 to 2019Enrolled2,000ConditionsHIVArmsIncentivised network delivery of HIV-ST, Peer navigator delivery of HIV-ST, standard of care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Oluwafemi Atanda AdeagboAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.ORCID 0000-0003-1462-9275
Nondumiso MthiyaneAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Carina HerbstAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Paul MeeEpidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
Melissa NeumanEpidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
Jaco DreyerAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Natsayi ChimbindiAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Theresa SmitAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Nonhlanhla OkesolaAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Cheryl JohnsonDepartment of HIV/AIDS, World Health Organization, Geneva, Switzerland.
Karin HatzoldPopulation Services International, Harare, Zimbabwe.
Janet SeeleyAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Frances CowanInternational Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Liz CorbettInfectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Maryam ShahmaneshAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa m.shahmanesh@ucl.ac.uk.
Africa Health Research Institute · ZALondon School of Hygiene & Tropical Medicine · GBLiverpool School of Tropical Medicine · GBUniversity of Johannesburg · ZAWorld Health Organization · CH

Funding

Maximizing combination HIV prevention, uptake and retention by adolescent girls and young womenR01MH114560 · NIMH · KWAZULU-NATAL RESEARCH INSTITUTE TB-HIV · PI SHAHMANESH, MARYAM · 2017 to 2023
$2.0M
Medical Research Council MR/R010161/1NIMH NIH HHS R01 MH114560Wellcome Trust 082384/Z/07/ZWellcome Trust 200901/Z/16/ZWorld Health Organization 001
6 · The paper itself

Abstract

introductionA cluster randomised controlled trial (cRCT) to determine whether HIV self-testing (HIVST) delivered by peers either directly or through incentivised peer-networks, could increase the uptake of antiretroviral therapy and pre-exposure prophylaxis (PrEP) among young women (18 to 24 years) is being undertaken in an HIV hyperendemic area in KwaZulu-Natal, South Africa. METHODS AND ANALYSIS: A three-arm cRCT started mid-March 2019, in 24 areas in rural KwaZulu-Natal. Twenty-four pairs of peer navigators working with ~12 000 young people aged 18 to 30 years over a period of 6 months were randomised to: (1) ETHICS AND DISSEMINATION: This study was approved by the Institutional Review Boards at the WHO, Switzerland (Protocol ID: STAR CRT, South Africa), London School of Hygiene and Tropical Medicine, UK (Reference: 15 990-1), University of KwaZulu-Natal (BFC311/18) and the KwaZulu-Natal Department of Health (Reference: KZ_201901_012), South Africa. The findings of this trial will be disseminated at local, regional and international meetings and through peer-reviewed publications. TRIAL REGISTRATION NUMBER: NCT03751826; Pre-results.

Indexed as

AdultAIDS SerodiagnosisCluster AnalysisFemaleHIV InfectionsHumansPeer GroupRandomized Controlled Trials as TopicRural PopulationSouth AfricaYoung AdultARTHIV/AIDSHIV self-testingpeer delivery modelPrEPSouth Africa

Identifiers

PMID31874891
PMCPMC7008432
OpenAlexW2997974779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.