ArticleJournal of clinical hypertension (Greenwich, Conn.)2020
The effects of hypertension and diabetes on new-onset chronic kidney disease: A prospective cohort study.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Incidence and predictors of diabetic kidney disease among type 2 diabetes mellitus adult patients in Ethiopia: a systematic review and meta-analysis.BMC endocrine disorders · 2025Pooled it
- Chronic kidney disease among patients with hypertension in sub-Saharan Africa: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Childhood modifiable risk factors and later life chronic kidney disease: a systematic review.BMC nephrology · 2023Pooled it
- Recommendations of the Brazilian Society of Nephrology for the management of chronic kidney disease in primary health care.Jornal brasileiro de nefrologiaGuideline
- Development and validation of a risk prediction model for chronic kidney disease among individuals with type 2 diabetes.Scientific reports · 2022Trial
- Association Between the Earliest CALLY Index at Diagnosis and Progression to End-Stage Kidney Disease in Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis.Medicina (Kaunas, Lithuania) · 2026Article
- Kidney Dysfunction-Associated Intracerebral Haemorrhage: Global Trends and Regional Disparities (1990-2021).Kidney & blood pressure research · 2026Article
- Observational
- Influence of Multiple Risk Factor Management on the Onset and Progression of Chronic Kidney Disease in Patients With Hypertension.Journal of the American Heart Association · 2025Article
- Association of quantitative renal surface nodularity with the renal dysfunction progression in patients with arterial hypertension.BMC medical imaging · 2025Article
- Impact of diabetes duration and hyperglycemia on the progression of diabetic kidney disease: Insights from the KNHANES 2019-2021.World journal of diabetes · 2025Article
- Global burden of anemia attributed to chronic kidney disease: prevalence, years lived with disability, and predictions to 2035 (Global burden of disease 2021).Frontiers in nutrition · 2025Article
- Interaction Effect of Depression and Hypertension on Nephrotoxicity Among Persons Living With HIV: A Cross-Sectional Study.International journal of nephrology · 2025Article
- Incidence of Proteinuria Post Radical Nephrectomy in Comparison to Partial Nephrectomy: A Comparative Study.Cureus · 2024Article
- The effect of different levels of systolic blood pressure control on new-onset chronic kidney disease in hypertension multimorbidity.Scientific reports · 2024Article
- A Study on Associations of Long Noncoding RNA HOTAIR Polymorphisms With Genetic Susceptibility to Chronic Kidney Disease.Journal of clinical laboratory analysis · 2024Article
- Article
- Article
- Global, regional, and national burden of chronic kidney disease attributable to high fasting plasma glucose from 1990 to 2019: a systematic analysis from the global burden of disease study 2019.Frontiers in endocrinology · 2024Article
- Leading Causes of Chronic Kidney Disease Among Dialysis Patients in Al-Baha Region, Saudi Arabia.Cureus · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aimed to determine the different status of hypertension and diabetes on the risk of new-onset chronic kidney disease (CKD) events in Kailuan Study. A total of 21 905 individuals were enrolled in the study. The new-onset incidents of CKD, hypertension, and diabetes were collected in the follow-ups. All the individuals were divided into five groups according to baseline and follow-up hypertension and diabetes status: baseline hypertension (BH), baseline hypertension and incidence of diabetes (BHID), baseline diabetes (BD), baseline diabetes and incidence of hypertension (BDIH), and baseline hypertension and diabetes (BHD). The risk of new-onset CKD of the five groups was calculated using the Cox regression analysis. In the median follow-up of 7.05 ± 2.59 years, the prevalence of new-onset CKD in the group of BH, BHID, BD, BDIH, and BHD were 27.1, 43.79, 25.4, 36.6, and 45.1 per 1000 years, respectively. When adjusted possible confounders, the hazard ratios (HRs) and 95% confidence intervals (CIs) of new-onset CKD were 1.50 (95% CI: 1.38-1.63), 1.25(95% CI: 1.07-1.47), and 1.52 (95% CI: 1.35-1.7) in the group of BHID, BDIH, and BHD, respectively, as referred to the BH group (P < .001). No obvious difference was observed in the group of BH and BD for the incidence of new-onset CKD. Sensitivity analysis still showed the similar results among the five groups. The study showed that the effect of simple hypertension or simple diabetes on new-onset CKD was not significantly different, but the incidence of new-onset hypertension or diabetes increased the risk of new-onset CKD. Hypertension and diabetes had a synergistic influence on the risk of new-onset CKD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.