Evidence map›Paper›PMID 31873839›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020

Reduction of radiation and contrast agent exposure in a cryoballoon ablation procedure with integration of electromagnetic mapping and intracardiac echocardiography: a single center experience.

Joyce Maalouf, Hoyle L Whiteside, Ajay Pillai, Abdullah Omar, Adam Berman, Samir Saba, Haitham Hreibe

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Safety and efficacy of intracardiac echocardiography in atrial fibrillation ablation: a meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Systematic Workflow and Electrogram guidance to reduce X-ray Exposure Time during cryoballoon ablation of atrial fibrillation: the SWEET-Cryo strategy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Intracardiac echocardiography Chinese expert consensus.Frontiers in cardiovascular medicine · 2022
    Review
  11. Article
  12. Acute Safety and Efficacy of Fluoroless Cryoballoon Ablation for Atrial Fibrillation.The Journal of innovations in cardiac rhythm management · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joyce MaaloufDivision of Cardiology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Hoyle L WhitesideDivision of Internal Medicine, Medical College of Georgia, Augusta University, 1120 15th Street , BBR B6518, Augusta, GA, 30912, USA.
Ajay PillaiDivision of Internal Medicine, Medical College of Georgia, Augusta University, 1120 15th Street , BBR B6518, Augusta, GA, 30912, USA.
Abdullah OmarDivision of Cardiology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Adam BermanDivision of Cardiology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Samir SabaHeart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Haitham HreibeDivision of Internal Medicine, Medical College of Georgia, Augusta University, 1120 15th Street , BBR B6518, Augusta, GA, 30912, USA. hhreibe@augusta.edu.ORCID http://orcid.org/0000-0002-4133-1960
Augusta University · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary vein isolation (PVI) with cryoballoon ablation (CBA) is routinely guided by fluoroscopy and utilizes contrast injection to ensure catheter positioning and pulmonary vein occlusion. Non-fluoroscopic imaging techniques including electromagnetic mapping (EM) and intracardiac echocardiography (ICE) have demonstrated reduced fluoroscopy times and contrast exposure. Utilization of color flow Doppler to evaluate vein occlusion with the balloon has not been evaluated as an alternative to contrast injection. In this study we evaluate the effectiveness of cryoablation guided by EM and ICE along with color Doppler to achieve PVI.

methodsWe designed a retrospective cohort study comparing patients who were treated before and after implementation of EM (Carto 3, Biosense Webster) and ICE during CBA (AF Solutions, Medtronic). We analyzed patients receiving CBA with fluoroscopy plus EM and ICE (group 2; N = 24) versus fluoroscopy alone (group 1; N = 25). Procedural success was defined as freedom from atrial fibrillation or other atrial arrhythmias at 1 year post ablation. Primary outcomes were radiation time and contrast exposure.

resultsProcedural success was achieved in all cases. Total fluoroscopy time was reduced from 22.4 ± 9.8 min to 8.9 ± 5.1 min (P < 0.001) in patients receiving CBA guided by EM and ICE. Furthermore, exposure to contrast media was significantly lower at 75.4 ± 24.1 ml and 16.5 ± 21.1 ml (P ≤ 0.001) in group 1 and group 2, respectively. Neither the number of required cryotherapy treatments nor procedure duration was negatively impacted by the implementation of non-fluoroscopic techniques. The 1-year success rate was identical between both groups at 72% and 79%. There was no difference in complication rates.

conclusionThis single-center cohort study demonstrates that CBA guided by EM and ICE can markedly reduce radiation and contrast exposure with excellent rates of acute PVI. This technique may be particularly effective in patients sensitive to intravenous contrast exposure.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryPulmonary VeinsContrast MediaEchocardiographyElectromagnetic PhenomenaFluoroscopyHumansRetrospective StudiesTreatment OutcomeContrast MediaCryoballoon ablationFluoroscopyPulmonary vein isolationRadiation exposure

Identifiers

PMID31873839
OpenAlexW2994906447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.