ArticleEJNMMI research2019
Quantification of myocardial
Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Chest X-ray-guided SPECT-only quantification as an adjunctive approach for wild-type transthyretin amyloid cardiomyopathy.Heart and vessels · 2026Article
- Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs.World journal of experimental medicine · 2026Review
- Quantification of amyloid deposition using bone scan agents.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Variability in bone-seeking tracers and imaging protocols for the diagnosis of cardiac amyloidosis: The more the merrier?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Quantitative SPECT/CT parameters of myocardialEJNMMI research · 2021Article
- Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Nuclear Imaging for the Diagnosis of Cardiac Amyloidosis in 2021.Diagnostics (Basel, Switzerland) · 2021Review
- 2021 Advocacy Statements for the Role ofActa Cardiologica Sinica · 2021Review
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to compare different methods for semi-quantitative analysis of cardiac retention of bone tracers in patients with cardiac transthyretin amyloidosis (ATTR).
methodsData from 67 patients with ATTR who underwent both conventional whole-body scan and a CZT myocardial SPECT (DSPECT, Spectrum Dynamics) 3 h after injection of
resultsH:Bs obtained from planar and reprojected data were not statistically different (wb-H:B, 2.05 ± 0.64, ant-H:B, 1.97 ± 0.61, LAO-H:B, 2.06 ± 0.64, all p = ns). However, 3D-H:B was increased compared to planar H:Bs (3D-H:B, 4.06 ± 1.77, all p < 0.0001 vs. wb-H:B, ant-H:B, and LAO-H:B). Bland-Altman plots demonstrated that the difference between 3D and planar H:Bs increased with the mean value of myocardial uptake. 3D-H:B was best correlated to septal thickness (r = 0.45, p < 0.001). Finally, abnormal right ventricular uptake was associated with higher values of cardiac retention.
conclusion3D semi-quantitative analysis of CZT SPECT optimized the assessment of
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