Evidence map›Paper›PMID 31873263›Full record

ArticleBritish dental journal2019

Oral antibiotic prescribing by NHS dentists in England 2010-2017.

Martin H Thornhill, Mark J Dayer, Michael J Durkin, Peter B Lockhart, Larry M Baddour

Open access · greenAbstract read
In one paragraph

Article in British dental journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Antibiotics to prevent complications following tooth extractions.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Stewardship of Antibiotics Prescribing in Belgian Dental Practice: A National Survey.International journal of environmental research and public health · 2026
    Article
  7. Article
  8. Review
  9. Article
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  12. Article
  13. Article
  14. Prescriber-level surveillance of outpatient antimicrobial consumption to enable targeted antimicrobial stewardship: a nationwide observational study, Switzerland, 2015 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Observational
  15. Endocarditis prevention: time for a review of NICE guidance.The Lancet regional health. Europe · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Martin H ThornhillUnit of Oral & Maxillofacial Medicine Surgery and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK; Department of Oral Medicine, Carolinas Medical Centre, Charlotte, NC, USA. m.thornhill@sheffield.ac.uk.
Mark J DayerDepartment of Cardiology, Taunton and Somerset NHS Trust, Taunton, Somerset, UK.
Michael J DurkinDivision of Infectious Diseases, Washington University in St. Louis School of Medicine, MO, USA.
Peter B LockhartDepartment of Oral Medicine, Carolinas Medical Centre, Charlotte, NC, USA.
Larry M BaddourDivision of Infectious Diseases, Department of Medicine and the Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
Carolinas Medical Center · USMayo Clinic · USTaunton & Somerset NHS Foundation Trust · GBWashington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
NCATS NIH HHS KL2 TR002346NCEZID CDC HHS U54 CK000609NIAID NIH HHS L30 AI133778
6 · The paper itself

Abstract

Introduction Dentists prescribe a significant proportion of all antibiotics, while antimicrobial stewardship aims to minimise antibiotic-prescribing to reduce the risk of developing antibiotic-resistance and adverse drug reactions.Aims To evaluate NHS antibiotic-prescribing practices of dentists in England between 2010-2017.Methods NHS Digital 2010-2017 data for England were analysed to quantify dental and general primary-care oral antibiotic prescribing.Results Dental prescribing accounted for 10.8% of all oral antibiotic prescribing, 18.4% of amoxicillin and 57.0% of metronidazole prescribing in primary care. Amoxicillin accounted for 64.8% of all oral antibiotic prescribing by dentists, followed by metronidazole (28.0%), erythromycin (4.4%), phenoxymethylpenicillin (0.9%), clindamycin (0.6%), co-amoxiclav (0.5%), cephalosporins (0.4%) and tetracyclines (0.3%). Prescriptions by dentists declined during the study period for all antibiotics except for co-amoxiclav. This increase is of concern given the need to restrict co-amoxiclav use to infections where there is no alternative. Dental prescribing of clindamycin, which accounted for 43.9% of primary care prescribing in 2010, accounted for only 14.6% in 2017. Overall oral antibiotic prescribing by dentists fell 24.4% as compared to 14.8% in all of primary care.Conclusions These data suggest dentists have reduced antibiotic prescribing, possibly more than in other areas of primary-care. Nonetheless, opportunities remain for further reduction.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipDentistsEnglandHumansInappropriate PrescribingPractice Patterns, Dentists'State MedicineAnti-Bacterial Agents

Identifiers

PMID31873263
PMCPMC7970513
OpenAlexW2998433052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.