Evidence map›Paper›PMID 31873186›Full record

ArticleScientific reports2019

Premotor dorsal white matter integrity for the prediction of upper limb motor impairment after stroke.

Leonardo Boccuni, Sarah Meyer, Nicholas D'cruz, Simon S Kessner, Lucio Marinelli, Carlo Trompetto, André Peeters, Vincent Van Pesch, Thierry Duprez, Stefan Sunaert and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Trial
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  8. Review
  9. Corticospinal premotor fibers facilitate complex motor control after stroke.Annals of clinical and translational neurology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leonardo BoccuniKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium. leonardo.boccuni@kuleuven.be.ORCID http://orcid.org/0000-0001-7385-5219
Sarah MeyerKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Nicholas D'cruzKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5306-5903
Simon S KessnerUniversity Medical Center Hamburg-Eppendorf, Department of Neurology, Hamburg, Germany.ORCID http://orcid.org/0000-0002-2051-8531
Lucio MarinelliUniversity of Genova, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Genova, Italy.ORCID http://orcid.org/0000-0003-0620-7654
Carlo TrompettoUniversity of Genova, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Genova, Italy.
André PeetersCliniques Universitaires Saint-Luc, Department of Neurology, Brussels, Belgium.
Vincent Van PeschCliniques Universitaires Saint-Luc, Department of Neurology, Brussels, Belgium.
Thierry DuprezCliniques Universitaires Saint-Luc, Department of Radiology, Brussels, Belgium.
Stefan SunaertKU Leuven - University of Leuven, Department of Imaging and Pathology, Leuven, Belgium.
Hilde FeysKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Vincent ThijsFlorey Institute of Neuroscience and Mental Health, Stroke Division, Melbourne, Australia.
Alice NieuwboerKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Geert VerheydenKU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corticospinal tract integrity after stroke has been widely investigated through the evaluation of fibres descending from the primary motor cortex. However, about half of the corticospinal tract is composed by sub-pathways descending from premotor and parietal areas, to which damage may play a more specific role in motor impairment and recovery, particularly post-stroke. Therefore, the main aim of this study was to investigate lesion load within corticospinal tract sub-pathways as predictors of upper limb motor impairment after stroke. Motor impairment (Fugl-Meyer Upper Extremity score) was evaluated in 27 participants at one week and six months after stroke, together with other clinical and demographic data. Neuroimaging data were obtained within the first week after stroke. Univariate regression analysis indicated that among all neural correlates, lesion load within premotor fibres explained the most variance in motor impairment at six months (R

Indexed as

FemaleHumansMaleMotor CortexMotor DisordersMultivariate AnalysisPyramidal TractsRegression AnalysisStrokeUpper ExtremityWhite Matter

Identifiers

PMID31873186
PMCPMC6928144

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.