Evidence map›Paper›PMID 31873110›Full record

ArticleScientific reports2019

A large self-transmissible resistance plasmid from Nigeria contains genes that ameliorate a carrying cost.

Rubén Monárrez, Molly Braun, Olivia Coburn-Flynn, João Botelho, Babatunde W Odetoyin, Jose I Otero-Vera, Naa Kwarley Eyiram Quartey, Luísa Peixe, Aaron O Aboderin, Iruka N Okeke

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. The metabolic burden associated with plasmid acquisition: An assessment of the unrecognized benefits to host cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Rubén MonárrezDepartment of Biology, Haverford College, Pennsylvania, USA.
Molly BraunDepartment of Biology, Haverford College, Pennsylvania, USA.
Olivia Coburn-FlynnDepartment of Biology, Haverford College, Pennsylvania, USA.
João BotelhoUCIBIO/REQUIMTE, Laboratory of Microbiology, Porto, Portugal.
Babatunde W OdetoyinDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo University, Ile-Ife, Nigeria.
Jose I Otero-VeraDepartment of Biology, Haverford College, Pennsylvania, USA.
Naa Kwarley Eyiram QuarteyDepartment of Biology, Haverford College, Pennsylvania, USA.
Luísa PeixeUCIBIO/REQUIMTE, Laboratory of Microbiology, Porto, Portugal.
Aaron O AboderinDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo University, Ile-Ife, Nigeria.
Iruka N OkekeDepartment of Biology, Haverford College, Pennsylvania, USA. iruka.n.okeke@gmail.com.ORCID http://orcid.org/0000-0002-1694-7587
Haverford College · USObafemi Awolowo University · NGRede de Química e Tecnologia · PT

Funding

RCUK | Medical Research Council (MRC) MR/L00464X/1
6 · The paper itself

Abstract

Antimicrobial resistance is rapidly expanding, in a large part due to mobile genetic elements. We screened 94 fecal fluoroquinolone-resistant Escherichia coli isolates from Nigeria for six plasmid-mediated quinolone resistance (PMQR) genes. Sixteen isolates harbored at least one of the PMQR genes and four were positive for aac-6-Ib-cr. In one strain, aac-6-Ib-cr was mapped to a 125 Kb self-transmissible IncFII plasmid, pMB2, which also bears bla

Indexed as

Conjugation, GeneticEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsDrug Resistance, BacterialFluoroquinolonesHumansMicrobial Sensitivity TestsNigeriaPlasmidsEscherichia coli ProteinsFluoroquinolones

Identifiers

PMID31873110
PMCPMC6927977
OpenAlexW2994736459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.