Trial reportScientific reports2019
Sensory-cognitive associations are only weakly mediated or moderated by social factors in the Canadian Longitudinal Study on Aging.
Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Functional social support and cognitive function in middle- and older-aged adults: a systematic review of cross-sectional and cohort studies.Systematic reviews · 2023Pooled it
- Pooled it
- Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Hearing Loss, Cognitive Decline, and Dementia: Clinical Intersections.Audiology research · 2026Review
- Psychosocial Function in Mild Cognitive Impairment: Social Participation is Associated With Cognitive Performance in Multiple Domains.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Profiles of social isolation and loneliness as moderators of the longitudinal association between uncorrected hearing impairment and cognitive aging.Communications psychology · 2025Article
- Visual Impairment and Cognitive Function in Aging Adults: Sex and Age Differences in Mediating Effect of Social Isolation and Depression.American journal of ophthalmology · 2025Article
- Sensory Deprivation in the Elderly Population of the Republic of Serbia: Sociodemographic Factors as Key to Understanding Sensory Challenges.Iranian journal of public health · 2024Article
- Depression, loneliness, and lower social activity as partial mediators of the association between visual impairment and cognitive decline.International journal of geriatric psychiatry · 2024Article
- Why Are Old-Age Disabilities Decreasing in Sweden and Denmark? Evidence on the Contribution of Cognition, Education, and Sensory Functions.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- The Longitudinal Association of Late-Life Visual and Hearing Difficulty and Cognitive Function: The Role of Social Isolation.Journal of aging and health · 2022Article
- Visual Impairment and Risk of Dementia in 2 Population-Based Prospective Cohorts: UK Biobank and EPIC-Norfolk.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness.Frontiers in neuroscience · 2022Article
- Vision Impairment and Participation in Cognitively Stimulating Activities: The Health ABC Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- The Association of Cognitive and Visual Function in a Nationally Representative Study of Older Adults in India.Neuroepidemiology · 2021Article
- Vision impairment and depression among older adults in low- and middle-income countries.International journal of geriatric psychiatry · 2021Article
- Brain Network Segregation and Glucose Energy Utilization: Relevance for Age-Related Differences in Cognitive Function.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Sensory and cognitive function both tend to decline with increasing age. Sensory impairments are risk factors for age-related cognitive decline and dementia. One hypothesis about sensory-cognitive associations is that sensory loss results in social isolation which, in turn, is a risk factor for cognitive decline. We tested whether social factors are associated with cognitive and sensory function, and whether sensory-cognitive associations are mediated or moderated by social factors. We used cross-sectional data from 30,029 participants in the Canadian Longitudinal Study of Aging, aged 45-85 years, who had no reported cognitive impairment or diagnosis of dementia. We found strong independent associations of self-reported social variables with hearing (pure-tone audiometry), vision (pinhole-corrected visual acuity), and executive function and weaker associations with memory. The moderating and mediating effects of social variables on sensory-cognitive associations were weak and mostly non-significant, but social factors could be slightly more important for females and older people. Partial retirement (relative to full retirement or not being retired) may have protective effects on cognition in the presence of hearing loss. These findings confirm the association between social factors and sensory and cognitive measures. However, support is weak for the hypothesis that social factors shape sensory-cognitive associations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.