ArticleClinical neuroradiology2020
Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion.
Article in Clinical neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Endovascular Treatment Combined With Standard Medical Treatment Improves Outcomes of Posterior Circulation Stroke: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Basilar Stenosis Reduces the Impact of Successful Recanalization on Outcome in Basilar Artery Occlusion.Diagnostics (Basel, Switzerland) · 2024Article
- Association of Procedure Time With Clinical and Procedural Outcome in Patients With Basilar Occlusion Undergoing Embolectomy.Neurology · 2023Article
- Outcomes Following Mechanical Thrombectomy in Different Etiological Subtypes of Acute Basilar Artery Occlusion : Stroke Etiology and Outcome after EVT in BAO.Clinical neuroradiology · 2023Article
- Time-Dependent Endovascular Treatment Effect According to Collateral Status in Basilar Artery Occlusion.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Article
- The impact of thrombus surface morphology of the basilar artery on the successful rate of mechanical thrombectomy.Frontiers in neurology · 2023Article
- CT Marker in Emergency Imaging of Acute Basilar Artery Occlusion: Thrombosis vs. Embolism.Diagnostics (Basel, Switzerland) · 2022Article
- Endovascular therapy in basilar artery occlusion in Sweden 2016-2019-a nationwide, prospective registry study.Neuroradiology · 2022Article
- Thrombectomy for Comatose Patients with Basilar Artery Occlusion : A Multicenter Study.Clinical neuroradiology · 2021Article
- Association of Regular Thrombus Surface Phenotype With Complete Recanalization in First-Line Contact Aspiration Thrombectomy for Basilar Artery Occlusion.Frontiers in neurology · 2021Article
- Predictors of Functional Outcome and Mortality in Endovascular Treatment for Acute Basilar Artery Occlusion: A Single-Centre Experience.Frontiers in neurology · 2021Article
- Predictors of Favorable Outcome after Endovascular Thrombectomy in MRI: Selected Patients with Acute Basilar Artery Occlusion.AJNR. American journal of neuroradiology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with basilar artery occlusion (BAO) were excluded from previous randomized controlled trials (RCTs) of endovascular treatment (ET) for acute ischemic stroke, but are commonly treated in clinical practice. This study aimed at analyzing predictors of functional outcome of ET in patients with BAO to improve patient selection for ET.
methodsConsecutive patients with BAO who received ET over a 2-year time period were prospectively studied. Baseline characteristics, procedural and outcome data were evaluated. Outcome was assessed by the modified Rankin Scale (mRS) 90 days after stroke. Multivariate regression analyses were performed to identify predictors of outcome across the range of the mRS, of poor outcome (mRS 5-6) and independent outcome (mRS 0-2).
resultsA total of 39 patients with BAO (median age: 75 years, 67% male) were included. Median baseline National Institutes of Health Stroke Scale (NIHSS) score was 24. Intravenous thrombolysis therapy (IVT) was administered in 56%. Successful recanalization assessed by a modified thrombolysis in cerebral infarction (TICI) score ≥2b was achieved in 82%. Independent outcome was observed in 30% of patients with successful recanalization, but in no patient with failed recanalization. Poor outcome was observed in 47% and 86%, respectively. Successful recanalization was associated with lower scores on the mRS at 90 days (p = 0.035), and failed recanalization was associated with an odds ratio of 13.6 for poor outcome (p = 0.036).
conclusionReperfusion is the major predictor of functional outcome in BAO in clinical practice. Failed recanalization resulted in a 13-fold increase of the risk of poor outcome. Successful recanalization is crucial to achieve a better functional outcome in BAO.
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