Evidence map›Paper›PMID 31872281›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Impact of body mass index on cardiac adrenergic derangement in heart failure patients: a

Klara Komici, Leonardo Bencivenga, Stefania Paolillo, Paola Gargiulo, Roberto Formisano, Roberta Assante, Carmela Nappi, Fabio Marsico, Adriana D'Antonio, Giovanni De Simini and 6 more

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. European journal of nuclear medicine and molecular imaging · 2023
    Review
  4. Dosing Therapeutic Radiopharmaceuticals in Obese Patients.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Klara KomiciDepartment of Medicine and Health Sciences, University of Molise, Campobasso, Italy.
Leonardo BencivengaDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Stefania PaolilloDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Paola GargiuloDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Roberto FormisanoIstituti Clinici Scientifici Maugeri SpA Società Benefit (ICS Maugeri SpA SB), Telese Terme, BN, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Carmela NappiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Fabio MarsicoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Adriana D'AntonioDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Giovanni De SiminiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Antonio CittadiniDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Dino Franco VitaleClinica San Michele, Via Appia 187, 81024, Maddaloni, CE, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Pasquale Perrone FilardiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Nicola FerraraDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy. giuseppe.rengo@unina.it.ORCID 0000-0002-9701-0437
University of Naples Federico II · ITIstituti Clinici Scientifici Maugeri · ITCasa di Cura San Michele · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the impact of body mass index (BMI) on cardiac adrenergic derangement, measured by iodine-123 meta-iodobenzylguanidine (

methodsWe prospectively enrolled patients with systolic HF, collecting demographic, clinical, echocardiographic data, and mIBG imaging parameters. In order to detect the factors associated with mIBG parameters, a model building strategy, based on the Multivariable Fractional Polynomial algorithm, has been employed.

resultsWe studied 249 patients with systolic HF, mean age of 66.4 ± 10.6 years, and mean left ventricular ejection fraction (LVEF) of 30.7% ± 6.4, undergoing cardiac

conclusionsResults of the present study indicate that BMI, together with LVEF and age, is independently correlated with cardiac mIBG uptake in HF patients.

Indexed as

3-IodobenzylguanidineBody Mass IndexHeartHeart FailureAgedFemaleHumansIodine RadioisotopesMaleMiddle AgedStroke VolumeVentricular Function, Left3-IodobenzylguanidineIodine-123Iodine Radioisotopes123I-mIBG imagingBody mass indexHeart failureSympathetic nervous system

Identifiers

PMID31872281
OpenAlexW2995023459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.