ReviewHeliyon2019
Regulation of L-proline biosynthesis, signal transduction, transport, accumulation and its vital role in plants during variable environmental conditions.
Review in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
153 citing papers in PubMed, 462 citations in OpenAlex.
- Proline: A Reliable Biochemical Marker of Plant Abiotic Stress Tolerance?Plants (Basel, Switzerland) · 2026Review
- Comprehensive Evaluation of the Physiological Responses and Cold Tolerance of Annual Shoots from Different Sweet Cherry (International journal of molecular sciences · 2026Article
- Long-Term Salt Exposure Reprograms the Nicotiana tabacum BY-2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments.Plant, cell & environment · 2026Article
- Mitochondrial vulnerability to aldehydic load and the role mitochondrial aldehyde dehydrogenases.Pharmacological research · 2026Review
- Metabolomic profiling of diatoms reveals distinct impacts of silver nanoparticles and ions.Environmental science. Nano · 2026Article
- A Highly EfficientPlants (Basel, Switzerland) · 2026Article
- AtGLYI3 and AtGLYI6 play the major role in nickel stress tolerance in Arabidopsis thaliana.Plant cell reports · 2026Article
- Royal jelly induces coordinated redox and energy metabolic responses in Candida guilliermondii NP-4.World journal of microbiology & biotechnology · 2026Article
- Compatible Solute Variation and Stress Adaptation in Native Qatari Plants: Focus on Proline.Life (Basel, Switzerland) · 2026Review
- Pre-sowing proline seed priming enhances germination, emergence, and antioxidant capacity of pepper under chilling stress.BMC plant biology · 2026Article
- Mitigation of salinity stress in Mentha piperita L. through foliar application of chitosan-salicylic acid encapsulated ZnO nanoparticles.Scientific reports · 2026Article
- Analysis of key nodes and metabolic pathways in the protein network of secondary metabolism in Panax quinquefolius L. enhanced by arbuscular mycorrhizal fungi.BMC plant biology · 2026Article
- Exogenous HProtoplasma · 2026Article
- Integrative multi-omics analysis reveals stress-specific molecular architectures in soybean under drought and rust infection.BMC genomics · 2026Article
- Study of the effects of photoselective shades on growth quality, nutrient absorption and biochemical indices of Polianthes (Polianthes tuberosa L.).Scientific reports · 2026Article
- Melatonin-Mediated Modulation of Metabolic Pathways Enhances Cold Tolerance in Alfalfa (Plants (Basel, Switzerland) · 2026Article
- Priority impacts of plant growth promoting fungi and proline under NaCl stress: boosting chickpea plants tolerance and performance.BMC plant biology · 2026Article
- Role of Altered Metabolites and Metabolic Pathways in Major Tuber Crops Under Drought Stress.Plant-environment interactions (Hoboken, N.J.) · 2026Review
- Proline Accumulation in Barley Under Salinity Is ABA-Independent, but Relies on the Level of Oxidative Stress When Modulated by Mo and W Ions.International journal of molecular sciences · 2026Article
- Spatiotemporal transcriptomic and metabolomic landscapes of wild soybean seed development reveal regulatory mechanisms of nutrient accumulation.Plant communications · 2026Article
93 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn response to various environmental stresses, many plant species synthesize L-proline in the cytosol and accumulates in the chloroplasts. L-Proline accumulation in plants is a well-recognized physiological reaction to osmotic stress prompted by salinity, drought and other abiotic stresses. L-Proline plays several protective functions such as osmoprotectant, stabilizing cellular structures, enzymes, and scavenging reactive oxygen species (ROS), and keeps up redox balance in adverse situations. In addition, ample-studied osmoprotective capacity, L-proline has been also ensnared in the regulation of plant improvement, including flowering, pollen, embryo, and leaf enlargement. SCOPE AND
conclusionsAlbeit, ample is now well-known about L-proline metabolism, but certain characteristics of its biological roles are still indistinct. In the present review, we discuss the L-proline accumulation, metabolism, signaling, transport and regulation in the plants. We also discuss the effects of exogenous L-proline during different environmental conditions. L-Proline biosynthesis and catabolism are controlled by several cellular mechanisms, of which we identify only very fewer mechanisms. So, in the future, there is a requirement to identify such types of cellular mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.