Evidence map›Paper›PMID 31872085›Full record

ArticlePhysics and imaging in radiation oncology2018

Remote beam output audits: a global assessment of results out of tolerance.

Stephen F Kry, Christine B Peterson, Rebecca M Howell, Joanna Izewska, Jessica Lye, Catharine H Clark, Mitsuhiro Nakamura, Coen Hurkmans, Paola Alvarez, Andrew Alves and 10 more

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Stephen F KryImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Christine B PetersonDepartment of Biostatistics, MD Anderson Cancer Center, Houston USA.
Rebecca M HowellDepartment of Radiation Physics, MD Anderson Cancer Center, Houston USA.
Joanna IzewskaDosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Vienna Austria.
Jessica LyeAustralian Clinical Dosimetry Service, ARPANSA, Melbourne, Australia.
Catharine H ClarkRadioTherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, London UK.
Mitsuhiro NakamuraJCOG Division of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University.
Coen HurkmansEORTC Radiation Oncology Group, Brussels, Belgium.
Paola AlvarezImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Andrew AlvesAustralian Clinical Dosimetry Service, ARPANSA, Melbourne, Australia.
Tomislav BokulicDosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Vienna Austria.
David FollowillImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Pavel KazantsevDosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Vienna Austria.
Jessica LowensteinImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Andrea MolineuImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Jacob PalmerDepartment of Radiation Physics, MD Anderson Cancer Center, Houston USA.
Susan A SmithDepartment of Radiation Physics, MD Anderson Cancer Center, Houston USA.
Paige TaylorImaging and Radiation Oncology Core, MD Anderson Cancer Center, Houston USA.
Paulina WesolowskaDosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Vienna Austria.
Ivan WilliamsAustralian Clinical Dosimetry Service, ARPANSA, Melbourne, Australia.

Funding

IROC: Enhancing local enrolling site radiological data capture capabilities for NCTN trialsU24CA180803 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI Thomas J. FitzGerald, MICHAEL V KNOPP · 2014 to 2026
$116.2M
Correcting Dose Calculation Errors in Radiation OncologyR01CA214526 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KRY, STEPHEN F · 2017 to 2020
$594k
NCI NIH HHS R01 CA214526NCI NIH HHS U24 CA180803
6 · The paper itself

Abstract

background and purposeRemote beam output audits, which independently measure an institution's machine calibration, are a common component of independent radiotherapy peer review. This work reviews the results and trends of these audit results across several organisations and geographical regions. MATERIALS AND

methodsBeam output audit results from the Australian Clinical Dosimetry Services, International Atomic Energy Agency, Imaging and Radiation Oncology Core, and Radiation Dosimetry Services were evaluated from 2010 to the present. The rate of audit results outside a +/-5% tolerance was evaluated for photon and electron beams as a function of the year of irradiation and nominal beam energy. Additionally, examples of confirmed calibration errors were examined to provide guidance to clinical physicists and auditing bodies.

resultsOf the 210,167 audit results, 1323 (0.63%) were outside of tolerance. There was a clear trend of improved audit performance for more recent dates, and while all photon energies generally showed uniform rates of results out of tolerance, low (6 MeV) and high (≥18 MeV) energy electron beams showed significantly elevated rates. Twenty nine confirmed calibration errors were explored and attributed to a range of issues, such as equipment failures, errors in setup, and errors in performing the clinical reference calibration. Forty-two percent of these confirmed errors were detected during ongoing periodic monitoring, and not at the time of the first audit of the machine.

conclusionsRemote beam output audits have identified, and continue to identify, numerous and often substantial beam calibration errors.

Indexed as

calibrationdosimetry auditGlobal harmonization groupQAremote beam output audit

Identifiers

PMID31872085
PMCPMC6927685

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.