Evidence map›Paper›PMID 31872067›Full record

ArticleNPJ digital medicine2019

Preventing inpatient falls with injuries using integrative machine learning prediction: a cohort study.

Lin Wang, Zhong Xue, Chika F Ezeana, Mamta Puppala, Shenyi Chen, Rebecca L Danforth, Xiaohui Yu, Tiancheng He, Mark L Vassallo, Stephen T C Wong

Abstract read
In one paragraph

Article in NPJ digital medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lin Wang1Bioinformatics and Biostatistics Cores and Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston, TX 77030 USA.
Zhong Xue1Bioinformatics and Biostatistics Cores and Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston, TX 77030 USA.
Chika F Ezeana2Department of Informatics Development, Houston Methodist Hospital, Houston, TX 77030 USA.
Mamta Puppala2Department of Informatics Development, Houston Methodist Hospital, Houston, TX 77030 USA.
Shenyi Chen2Department of Informatics Development, Houston Methodist Hospital, Houston, TX 77030 USA.
Rebecca L Danforth1Bioinformatics and Biostatistics Cores and Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston, TX 77030 USA.
Xiaohui Yu2Department of Informatics Development, Houston Methodist Hospital, Houston, TX 77030 USA.
Tiancheng He2Department of Informatics Development, Houston Methodist Hospital, Houston, TX 77030 USA.ORCID 0000-0003-3543-5701
Mark L Vassallo3Department of Quality Operations, Houston Methodist Hospital, Houston, TX 77030 USA.
Stephen T C Wong1Bioinformatics and Biostatistics Cores and Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Houston, TX 77030 USA.ORCID 0000-0001-9188-6502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient falls during hospitalization can lead to severe injuries and remain one of the most vexing patient-safety problems facing hospitals. They lead to increased medical care costs, lengthened hospital stays, more litigation, and even death. Existing methods and technology to address this problem mostly focus on stratifying inpatients at risk, without predicting fall severity or injuries. Here, a retrospective cohort study was designed and performed to predict the severity of inpatient falls, based on a machine learning classifier integrating multi-view ensemble learning and model-based missing data imputation method. As input, over two thousand inpatient fall patients' demographic characteristics, diagnoses, procedural data, and bone density measurements were retrieved from the HMH clinical data warehouse from two separate time periods. The predictive classifier developed based on multi-view ensemble learning with missing values (MELMV) outperformed other three baseline models; achieved a cross-validated AUC of 0.713 (95% CI, 0.701-0.725), an AUC of 0.808 (95% CI, 0.740-0.876) on the separate testing set. Our studies show the efficacy of integrative machine-learning based classifier model in dealing with multi-source patient data, which in this case delivers robust predictive performance on the severity of patient falls. The severe fall index provided by the MELMV classifier is calculated to identify inpatients who are at risk of having severe injuries if they fall, thus triggering additional steps of intervention to prevent a harmful fall, beyond the standard-of-care procedure for all high-risk fall patients.

Indexed as

Disease preventionRisk factors

Identifiers

PMID31872067
PMCPMC6908660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.