Evidence map›Paper›PMID 31871929›Full record

ArticleBioMed research international2019

Molecular Mechanism of Matrine from

Zhi Chen, Nobuhiro Nishimura, Takayuki Okamoto, Koichiro Wada, Kohji Naora

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Research Advances on Matrine.Frontiers in chemistry · 2022
    Review
  5. Biological Activity of Naturally Derived Naphthyridines.Molecules (Basel, Switzerland) · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zhi ChenDepartment of Pharmacy, Shimane University Hospital, Izumo, Shimane, Japan.ORCID https://orcid.org/0000-0002-7624-3143
Nobuhiro NishimuraDepartment of Pharmacy, Shimane University Hospital, Izumo, Shimane, Japan.ORCID https://orcid.org/0000-0003-2255-9748
Takayuki OkamotoDepartment of Pharmacology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Koichiro WadaDepartment of Pharmacology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.ORCID https://orcid.org/0000-0001-9231-0556
Kohji NaoraDepartment of Pharmacy, Shimane University Hospital, Izumo, Shimane, Japan.ORCID https://orcid.org/0000-0001-6624-0291
Shimane University · JPFukuoka International University · JPShimane University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance is the main obstacle to current chemotherapies. In this study, we evaluated the reversing effect of matrine, the principal alkaloid derived from

Indexed as

AlkaloidsAntineoplastic AgentsApoptosisATP Binding Cassette Transporter, Subfamily BCell SurvivalDoxorubicinDrug Resistance, MultipleDrug Resistance, NeoplasmHumansInhibitory Concentration 50K562 CellsLeukemiaMatrinesNF-kappa BQuinolizinesSophoraABCB1 protein, humanAlkaloidsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily BDoxorubicinMatrinesNF-kappa BQuinolizines

Identifiers

PMID31871929
PMCPMC6906886
OpenAlexW2990650024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.